De Quervain's Tenosynovitis: A common condition that affects the tendons on the thumb side of the wrist, leading to pain and limited mobility of the thumb. It is often caused by repetitive movements or direct injury to the area.

Trigger Thumb: A condition where the thumb tendon becomes inflamed, causing the thumb to catch or lock when extended or flexed, leading to limited mobility.
Thumb Osteoarthritis: Wear and tear on the joints of the thumb, leading to pain, stiffness, and limited mobility.
Thumb Sprain: An injury to the ligaments surrounding the thumb joint, causing pain, swelling, and limited mobility.

Ganglion Cyst: A non-cancerous lump that can develop on the wrist or thumb, causing pain, numbness, and limited mobility. If left untreated, it can lead to nerve damage or infection.
Thumb Fracture: A break in one of the bones of the thumb, which can cause severe pain, swelling, and limited mobility. If not properly diagnosed and treated, it can lead to long-term disability or deformity.
Infection (e.g., Cellulitis or Abscess): Bacterial infections that can cause redness, swelling, pain, and limited mobility of the thumb. If left untreated, it can lead to serious complications, such as sepsis or amputation.

Thumb Tendinosis: A degenerative condition that affects the tendons of the thumb, causing pain and limited mobility.
Gamekeeper's Thumb (Ulnar Collateral Ligament Injury): A rare injury to the ligament that connects the thumb to the hand, causing pain, instability, and limited mobility.
Kienbock's Disease: A rare condition that affects the blood supply to the lunate bone in the wrist, causing pain, stiffness, and limited mobility of the thumb.