What is the recommended vaccine schedule for children and adults?

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Last updated: September 28, 2025View editorial policy

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Recommended Vaccine Schedules for Children and Adults

The American Academy of Pediatrics (AAP) recommends a comprehensive vaccination schedule for all infants, children, and adults, with specific timing for each vaccine to maximize protection against vaccine-preventable diseases and reduce morbidity and mortality. 1

Childhood Vaccination Schedule (0-18 years)

Birth to 6 Months

  • Hepatitis B (HepB): First dose within 24 hours of birth, second dose at 1-2 months, third dose at 6-18 months 1, 2
  • Rotavirus (RV): First dose at 2 months, second dose at 4 months, must start by 12 weeks of age and complete by 32 weeks 1
  • Diphtheria, Tetanus, acellular Pertussis (DTaP): First dose at 2 months, second dose at 4 months, third dose at 6 months 1
  • Haemophilus influenzae type b (Hib): First dose at 2 months, second dose at 4 months, third dose at 6 months (if using PRP-OMP [PedvaxHIB], third dose may not be required) 1
  • Pneumococcal conjugate (PCV): First dose at 2 months, second dose at 4 months, third dose at 6 months 1
  • Inactivated Poliovirus (IPV): First dose at 2 months, second dose at 4 months 1

6-18 Months

  • Influenza: Annual vaccination starting at 6 months; children under 8 years receiving influenza vaccine for the first time should receive two doses separated by at least 4 weeks 1, 3
  • IPV: Third dose at 6-18 months 1

12-15 Months

  • MMR (Measles, Mumps, Rubella): First dose at 12-15 months 1, 3
  • Varicella: First dose at 12-15 months 1, 3
  • Hepatitis A (HepA): First dose at 12 months 1, 3
  • Hib: Final booster dose at 12-15 months 1
  • PCV: Final dose at 12-15 months 1

15-18 Months

  • DTaP: Fourth dose at 15-18 months 1

4-6 Years

  • DTaP: Fifth and final dose in the series 1, 3
  • IPV: Fourth and final dose 1, 3
  • MMR: Second dose 3
  • Varicella: Second dose 3

11-12 Years

  • Tdap: One dose 1
  • Human papillomavirus (HPV): Two-dose series 1, 3
  • Meningococcal conjugate (MenACWY): First dose 1, 3

16 Years

  • MenACWY: Second dose (booster) 1
  • Meningococcal B (MenB): Two-dose series may be administered based on clinical discretion for ages 16-23 years 1, 4

Adult Vaccination Schedule

  • Influenza: Annual vaccination 1
  • Tdap/Td: Tdap once, then Td or Tdap booster every 10 years 1
  • HPV: Recommended through age 26 if not adequately vaccinated previously 1
  • Pneumococcal: Based on age and risk factors 1
  • Hepatitis A and B: For those not previously vaccinated and at risk 1
  • MMR: For adults born after 1957 without evidence of immunity 1
  • Varicella: For adults without evidence of immunity 1

Special Considerations

Pregnant Women

  • Tdap: One dose during each pregnancy, preferably between 27-36 weeks gestation 1, 4
  • Influenza: Recommended during flu season 1

Catch-up Vaccination

  • For children and adolescents who start late or are >1 month behind, follow catch-up schedules to bring them current with recommended vaccines 1, 4
  • A vaccine series does not need to be restarted, regardless of the time elapsed between doses 1

High-Risk Groups

  • Children with specific medical conditions may require additional vaccines or modified schedules 4
  • Hemodialysis patients require higher doses of certain vaccines, such as hepatitis B 2
  • Children with asplenia, complement deficiencies, or HIV infection have specific recommendations for meningococcal vaccination 4

Common Pitfalls in Vaccine Administration

  1. Missing opportunities for simultaneous administration: When multiple vaccines are due, they should be given during the same visit 1
  2. Restarting vaccine series unnecessarily: A series never needs to be restarted, regardless of time elapsed between doses 1
  3. Not following catch-up schedules: Children who are behind should be brought up-to-date as quickly as possible following minimum interval guidelines 1
  4. Delaying vaccines without medical indication: This leaves children vulnerable to preventable diseases 5
  5. Improper storage or administration technique: Can reduce vaccine efficacy 2

Vaccination Coverage and Importance

National vaccination coverage by age 24 months is at least 90% for poliovirus vaccine, MMR, hepatitis B, and varicella, although MMR coverage is below 90% in 20 states 5. Only 1.3% of children born in 2015 and 2016 had received no vaccinations by their second birthday 5. Maintaining high vaccination rates is crucial for preventing outbreaks of vaccine-preventable diseases.

References

Guideline

Vaccination Schedule Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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