Treatment of Stasis Dermatitis
The cornerstone treatment for stasis dermatitis includes compression therapy to address the underlying venous hypertension, combined with topical anti-inflammatory agents and proper skin care. 1, 2
First-Line Management
Compression Therapy
- Essential first-line treatment to improve venous return and reduce edema
- Options include:
- Compression stockings (20-30 mmHg or 30-40 mmHg)
- Multilayer bandaging systems
- Pneumatic compression devices for severe cases
- Elevate affected limbs to promote gravity drainage of edema 1
Skin Care and Moisturization
- Apply fragrance-free, hypoallergenic moisturizers multiple times daily
- Look for products containing petrolatum or mineral oil
- Apply immediately after bathing while skin is still damp
- Use "soak and smear" technique for severe cases:
- Soak affected area in plain water for 20 minutes
- Apply moisturizer to damp skin 1
- Use dispersible cream as soap substitute instead of regular soaps/detergents 1
- Pat dry gently rather than rubbing the skin 1
Topical Anti-inflammatory Therapy
- Topical corticosteroids for acute flares:
- Medium to high potency for short courses (2 weeks maximum)
- Apply after moisturizer for better penetration
- Caution: limit use to avoid skin atrophy 1
- Topical calcineurin inhibitors (tacrolimus 0.1% ointment) may be effective:
Management of Complications
Secondary Infection
- Consider topical antimicrobials for suspected secondary infection:
- Clindamycin 2% or erythromycin 1% cream
- Take bacterial swabs if infection is suspected 1
- Use oral antibiotics if signs of systemic infection are present:
- Penicillinase-resistant penicillin or first-generation cephalosporin
- Consider clindamycin, doxycycline, or SMX-TMP for MRSA concerns 1
Extensive Disease
- For extensive involvement (>20% body surface area):
- Consider short course of systemic steroids
- May provide relief within 12-24 hours 1
- For recalcitrant cases:
- Consider phototherapy (narrowband UVB)
- May need referral to dermatologist for other systemic therapy options 1
Addressing Underlying Venous Insufficiency
- Interventional options for correcting venous reflux:
- Endovenous thermal ablation
- Ultrasound-guided foam sclerotherapy
- Surgical options for severe cases 5
- Consultation with vascular specialist recommended for persistent cases
Follow-up and Prevention
- Maintain compression therapy even after acute phase resolves 1
- Continue daily moisturizing to prevent skin dryness and cracking 1
- Monitor for signs of topical steroid side effects (skin atrophy, telangiectasia) 1
- Patient education is crucial for compliance with compression therapy 4
Common Pitfalls to Avoid
- Overlooking continued exposure to irritants
- Inadequate moisturization
- Overuse of topical steroids leading to skin atrophy
- Missing secondary infection
- Failure to address underlying venous insufficiency 1
- Not considering contact sensitization, which is more common in stasis dermatitis patients 4
Stasis dermatitis management requires addressing both the underlying venous hypertension and the resulting inflammatory skin changes. Compression therapy remains the foundation of treatment, with topical anti-inflammatory agents and proper skin care as important adjuncts.