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Last updated: September 28, 2025View editorial policy

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Differential Diagnosis for Residence over the Longs upon Percussion

  • Single most likely diagnosis
    • Pneumothorax: This condition is the most likely diagnosis because a resonant or hyper-resonant sound upon percussion over the lung fields can indicate the presence of air in the pleural space, which is a hallmark of pneumothorax.
  • Other Likely diagnoses
    • Pulmonary embolism: While not as directly related to percussion findings, pulmonary embolism can lead to areas of lung that are not functioning properly, potentially altering percussion sounds.
    • Chronic obstructive pulmonary disease (COPD): COPD can lead to hyperinflation of the lungs, which might result in a more resonant sound upon percussion due to the increased air trapping.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Tension pneumothorax: This is a life-threatening condition that requires immediate recognition and treatment. It can present with shifted trachea, decreased breath sounds on the affected side, and hyper-resonance to percussion.
    • Asthma exacerbation: In severe cases, asthma can lead to significant air trapping and hyperinflation, potentially mimicking the percussion findings of other conditions.
  • Rare diagnoses
    • Cystic fibrosis: This chronic condition can lead to bronchiectasis and hyperinflation of the lungs, potentially altering percussion sounds, but it's less likely to present acutely with changes in percussion over the longs.
    • Congenital bullous emphysema: A rare condition that could potentially cause localized hyper-resonance due to large bullae, but it's much less common and typically presents in infancy or early childhood.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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