Immune Thrombocytopenic Purpura (ITP): This condition is characterized by autoimmune destruction of platelets, leading to a low platelet count. It is a common cause of thrombocytopenia and often presents with a platelet count in the range of 50-100k.

Viral Infections (e.g., HIV, Hepatitis C): Certain viral infections can lead to thrombocytopenia due to bone marrow suppression or immune-mediated platelet destruction.
Medication-Induced Thrombocytopenia: Various medications, such as heparin, quinine, and sulfonamides, can cause thrombocytopenia as a side effect.
Chronic Liver Disease: Liver disease can lead to thrombocytopenia due to splenic sequestration and decreased platelet production.

Thrombotic Thrombocytopenic Purpura (TTP): A rare but life-threatening condition characterized by thrombocytopenia, microangiopathic hemolytic anemia, and renal failure. Prompt diagnosis and treatment are crucial to prevent mortality.
Heparin-Induced Thrombocytopenia (HIT): A serious condition that occurs in response to heparin therapy, leading to thrombocytopenia and increased risk of thrombosis.
Disseminated Intravascular Coagulation (DIC): A condition characterized by widespread clotting and bleeding, which can lead to thrombocytopenia and other coagulopathy abnormalities.

Congenital Thrombocytopenias (e.g., Bernard-Soulier Syndrome, Wiskott-Aldrich Syndrome): Rare genetic disorders that affect platelet production or function.
Bone Marrow Failure Syndromes (e.g., Aplastic Anemia, Myelodysplastic Syndromes): Conditions that affect the bone marrow's ability to produce blood cells, including platelets.
Systemic Lupus Erythematosus (SLE): A chronic autoimmune disease that can cause thrombocytopenia, among other symptoms.