Management of Peritonsillar Abscess with Airway Compromise
Immediate airway management with rapid sequence intubation by the most experienced clinician is required for a patient with peritonsillar abscess presenting with difficulty breathing and drooling, as these are signs of impending airway obstruction.
Initial Assessment and Stabilization
Signs of Airway Compromise
- Difficulty breathing
- Drooling
- Other concerning signs may include:
- Stridor
- "Hot potato" voice
- Trismus (limited mouth opening)
- Dysphagia
- Muffled voice
Immediate Actions
- Call for help immediately - summon the most experienced airway manager available 1
- Position the patient - upright position if tolerated to maximize airway patency
- Administer supplemental oxygen - high-flow oxygen via face mask
- Prepare for definitive airway management - this is not a "wait and see" situation
Definitive Airway Management
Equipment Preparation
- Prepare for rapid sequence intubation (RSI)
- Have difficult airway equipment immediately available:
- Video laryngoscope (preferred first-line device)
- Bougie
- Supraglottic airway devices (second-generation preferred)
- Surgical airway equipment (scalpel-bougie-tube)
Intubation Approach
RSI by most experienced clinician 1
- Consider modified RSI with maintenance of spontaneous ventilation if severe obstruction
- Avoid multiple attempts - transition through algorithm promptly if difficulty encountered
- Use video laryngoscopy if available to improve first-pass success
If intubation fails:
- Attempt supraglottic airway (SGA) placement
- If SGA fails, move quickly to surgical airway (front-of-neck access)
- Follow the "can't intubate, can't oxygenate" protocol 1
Special Considerations
- Avoid nasotracheal intubation due to increased stimulation of airway reflexes 2
- Consider awake intubation only if patient is stable, cooperative, and has minimal airway edema 1
- Have surgical backup ready for emergency surgical airway if needed
Post-Intubation Management
Confirm tube placement with continuous waveform capnography
Secure the tube and record depth of insertion
Administer antibiotics effective against group A streptococcus and oral anaerobes 3, 4
- Penicillin plus metronidazole
- Clindamycin
- Appropriate cephalosporins
Abscess drainage once airway is secured:
Supportive care:
- IV hydration
- Pain control
- Consider corticosteroids to reduce inflammation and speed recovery 4
Complications to Monitor
- Extension of infection into deep neck spaces
- Aspiration
- Sepsis
- Mediastinitis
- Jugular vein thrombosis
Common Pitfalls to Avoid
- Delayed recognition of airway compromise - drooling and respiratory distress are late signs requiring immediate action
- Multiple intubation attempts - limit attempts and progress through algorithm quickly
- Inadequate preparation - always have difficult airway equipment and surgical backup ready
- Inappropriate antibiotic selection - must cover both aerobic and anaerobic organisms
Remember that peritonsillar abscess with airway compromise represents a true emergency. The priority is securing the airway before proceeding with definitive treatment of the abscess itself.