Depression or Anxiety: These conditions are common in middle-aged women and can manifest with memory lapses due to decreased attention and concentration. Stress and emotional distress can significantly impact cognitive function, leading to subjective reports of memory problems.

Sleep Disorders: Conditions like insomnia, sleep apnea, or restless leg syndrome can lead to fatigue, which impairs cognitive function, including memory.
Hypothyroidism: This condition is more common in women and can cause cognitive symptoms, including memory lapses and difficulty concentrating.
Vitamin B12 Deficiency: A deficiency in vitamin B12 can lead to neurological symptoms, including memory loss, and is more common in individuals with dietary restrictions or malabsorption issues.
Medication Side Effects: Various medications, such as sedatives, antidepressants, and antihistamines, can cause memory lapses as a side effect.

Transient Ischemic Attack (TIA) or Stroke: Although less common in younger individuals, a TIA or stroke can cause sudden memory lapses and must be ruled out due to their potential for severe consequences and the need for immediate intervention.
Brain Tumors: While rare, brain tumors can cause cognitive symptoms, including memory loss, and are critical to diagnose early for effective treatment.
Infections like Meningitis or Encephalitis: These conditions are medical emergencies that can present with cognitive symptoms, including memory lapses, and require prompt diagnosis and treatment.
Chronic Traumatic Encephalopathy (CTE): In individuals with a history of repetitive head trauma, CTE could be a consideration, though it's more commonly associated with older age and a longer history of trauma.

Early-Onset Alzheimer's Disease: Although rare in individuals under 50, early-onset Alzheimer's can occur and should be considered if other causes are ruled out and cognitive decline progresses.
Frontotemporal Dementia: A group of brain disorders caused by cell degeneration in the brain's frontal and temporal lobes, leading to changes in personality, behavior, and language, but can also include memory symptoms.
Creutzfeldt-Jakob Disease: A rare, degenerative, fatal brain disorder that can cause memory loss, among other neurological symptoms.
Wilson's Disease: A genetic disorder that leads to copper accumulation in the brain and liver, causing neurological symptoms, including cognitive decline and memory lapses, though it typically presents at a younger age.