What is the treatment for anosmia (loss of smell)?

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Last updated: March 19, 2025View editorial policy

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From the Guidelines

Treatment for anosmia, or loss of smell, should prioritize smell training, which involves sniffing four distinct scents for 20 seconds each, twice daily for at least 3-6 months, as it has shown promise in improving olfaction in post-viral anosmia, including COVID-19 related smell loss 1. When considering treatment for anosmia, it is essential to determine the underlying cause, as this will guide the most effective management strategy.

  • For anosmia caused by nasal congestion from colds, allergies, or sinusitis, decongestants like pseudoephedrine or nasal steroid sprays such as fluticasone may help, along with saline nasal irrigation using a neti pot twice daily.
  • For post-viral anosmia, including COVID-19 related smell loss, smell training is recommended, as supported by studies such as Abdelalim et al. (2021) and Mohamad et al. (2021) 1.
  • For anosmia due to nasal polyps, oral corticosteroids like prednisone may be prescribed, followed by nasal steroid sprays. Some cases of anosmia, particularly those caused by head trauma or neurological conditions, may be permanent.
  • Treatment works best when started early, as prolonged smell loss can lead to nerve damage that becomes irreversible.
  • If anosmia persists beyond two weeks or occurs without an obvious cause, medical evaluation is necessary to determine the underlying cause and appropriate treatment, as suggested by the study by Addison et al. (2021) 1. It is crucial to note that the current evidence is limited, and more research is needed to fully understand the effectiveness of different treatments for anosmia, as highlighted in the study by Lechner et al. (2020) 1.

From the Research

Treatment Options for Anosmia

  • The treatment for anosmia, or loss of smell, can vary depending on the underlying cause of the condition 2, 3.
  • According to a systematic review, treatments with the most robust data for anosmia include:
    • Intranasal corticosteroids
    • Olfactory training
  • Olfactory training is a recommended treatment for post-viral olfactory dysfunction, a common cause of anosmia 3.
  • The use of short-term systemic and/or topical steroids may be an option for select patients, but careful consideration of potential risks is necessary 3.
  • Other treatment options, such as systemic steroids, topical therapies, and acupuncture, have been studied, but the evidence is limited, and more research is needed to determine their effectiveness 2, 3.

Specific Treatments

  • Intranasal corticosteroids have been shown to be effective in improving olfactory function in patients with chronic rhinosinusitis, a common cause of anosmia 4.
  • Olfactory training, which involves repeated exposure to different odors, has been shown to improve olfactory function in patients with anosmia 2, 3.
  • Short-course oral steroids have been used as an adjunct therapy for chronic rhinosinusitis, but the evidence is limited, and more research is needed to determine their effectiveness 4.

Future Research Directions

  • Further research is needed to expand therapeutic options for anosmia and to determine the effectiveness of different treatments for this condition 2, 3.
  • Studies with longer follow-up periods and larger sample sizes are needed to fully understand the effects of different treatments on anosmia 4, 3.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Management of Post-Infectious Anosmia and Hyposmia: A Systematic Review.

The Annals of otology, rhinology, and laryngology, 2023

Research

Short-course oral steroids as an adjunct therapy for chronic rhinosinusitis.

The Cochrane database of systematic reviews, 2016

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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