Treatment Recommendations for Throat Pain
For throat pain, the primary treatment is symptomatic relief with analgesics such as ibuprofen (400mg every 6-8 hours) or paracetamol/acetaminophen (500-1000mg every 4-6 hours), with ibuprofen showing superior efficacy for pain relief. 1
First-Line Treatment Options
Systemic Analgesics
Ibuprofen:
Paracetamol/Acetaminophen:
- Adults: 500-1000mg every 4-6 hours (maximum 4000mg/day)
- Children: 10-15mg/kg every 4-6 hours
- Less effective than ibuprofen but still superior to placebo 4
Important caution: Aspirin should be avoided in children due to risk of Reye syndrome 1
Topical Treatments
Local anesthetics with confirmed efficacy:
Lozenges containing flurbiprofen 8.75mg:
- Can provide relief for pain intensity, difficulty swallowing, and throat swelling 3
- Can be taken up to five times daily (every 3-6 hours)
Treatment Algorithm
Assess severity and duration of symptoms:
- If severe throat pain with high fever, headache, nausea, or vomiting, refer to physician immediately 5
- If mild to moderate pain without concerning symptoms, proceed with symptomatic treatment
First-line treatment:
- Begin with systemic analgesics (ibuprofen preferred over acetaminophen)
- Consider adding topical anesthetics for additional relief
For persistent symptoms:
Special Considerations
Duration of treatment: Do not use topical treatments for more than 2 days without medical consultation 5
Bacterial vs. viral etiology:
Supportive measures:
Common Pitfalls to Avoid
Overuse of antibiotics: Throat infections are predominantly viral; antibiotics should be reserved for confirmed bacterial infections 6
Inadequate pain control: Pain from throat inflammation can be severe and requires appropriate dosing of analgesics 7
Delayed medical attention: Severe or persistent sore throat with fever, headache, nausea, or vomiting requires prompt medical evaluation 5
Using aspirin in children: This increases risk of Reye syndrome 1
Relying solely on topical treatments: Systemic analgesics provide more comprehensive relief and should be the foundation of treatment 1, 2