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Differential Diagnosis for Wedged Shaped Opacity Arising from the Left Hilum/Mediastinum on X-ray

  • Single Most Likely Diagnosis
    • Pulmonary embolism with infarction: This is a common cause of a wedge-shaped opacity, especially if it arises from the hilum and is associated with symptoms such as sudden onset of chest pain and shortness of breath.
  • Other Likely Diagnoses
    • Lung cancer: Tumors can present as a wedge-shaped opacity, especially if they are located centrally and invade or compress adjacent lung tissue.
    • Pulmonary metastasis: Similar to primary lung cancer, metastatic lesions can cause wedge-shaped opacities, particularly if they are located near the hilum.
    • Lymphadenopathy: Enlarged lymph nodes in the mediastinum or hilum can cause a wedge-shaped appearance on X-ray, especially if they are due to infection, inflammation, or malignancy.
  • Do Not Miss Diagnoses
    • Aortic dissection: Although less common, an aortic dissection can cause a wedge-shaped opacity if it involves the mediastinum and compresses or invades adjacent lung tissue. This is a medical emergency.
    • Mediastinal hematoma: Bleeding into the mediastinum, which could be traumatic or spontaneous, can cause a rapidly expanding mass that might appear as a wedge-shaped opacity on X-ray.
  • Rare Diagnoses
    • Diaphragmatic hernia: A rare condition where abdominal contents herniate into the thoracic cavity, potentially causing a wedge-shaped opacity if the hernia is large enough and involves the mediastinum or hilum.
    • Foregut duplication cysts: These are rare congenital anomalies that can present as a mass in the mediastinum and potentially cause a wedge-shaped opacity on X-ray if they become large enough or infected.
    • Mediastinal fibrosis: A rare condition characterized by the deposition of collagen and fibrous tissue within the mediastinum, which can cause masses or opacities that might appear wedge-shaped on X-ray.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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