What is the recommended approach for treating and presenting a patient with a trunk wart to the attending?

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Last updated: September 29, 2025View editorial policy

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Approach to Treating and Presenting a Patient with Trunk Wart

For trunk warts, cryotherapy with liquid nitrogen is the recommended first-line provider-administered treatment, with salicylic acid 15-26% as an alternative patient-applied option. 1

Clinical Assessment and Presentation to Attending

When presenting a trunk wart case to your attending, follow this structured approach:

1. Introduction

  • "I evaluated a [age] [gender] patient presenting with a [size, number, appearance] wart(s) on the trunk that has been present for [duration]."
  • Specify if there are any concerning features: bleeding, rapid growth, unusual pigmentation, or pain

2. Relevant History

  • Duration of the wart(s)
  • Previous treatments attempted and outcomes
  • Immunocompromised status (if applicable)
  • Impact on quality of life (pain, cosmetic concerns)

3. Physical Examination Findings

  • Precise location on trunk
  • Size and number of lesions
  • Appearance (flat, raised, pigmented, etc.)
  • Any surrounding skin changes

4. Treatment Plan

Present your treatment recommendation in this algorithmic approach:

First-Line Options:

  • Provider-administered treatment: Cryotherapy with liquid nitrogen

    • Applied every 1-2 weeks
    • Efficacy rate: 63-88% 1
    • Continue for 3-4 months if needed
  • Patient-applied alternative: Salicylic acid (15-26%)

    • Applied daily after paring for 3-4 months
    • Efficacy rate: comparable to cryotherapy for non-genital warts 1

Second-Line Options (if first-line fails):

  • Trichloroacetic acid (TCA) 80-90%

    • Applied weekly until resolved
    • Efficacy rate: 81% 1
  • Imiquimod 5% cream

    • Applied three times weekly at bedtime for up to 16 weeks
    • Efficacy rate: approximately 35% 1, 2

For Refractory Cases:

  • Surgical removal (93% clearance rate, but 29% recurrence) 1
  • Consider combination therapy (e.g., cryotherapy plus salicylic acid)

Key Points to Emphasize to Attending

  1. Treatment Monitoring: Change treatment if no substantial improvement after three provider-administered treatments or if warts haven't cleared after six treatments 3

  2. Patient Education:

    • Spontaneous resolution occurs in 20-30% of cases within 3 months 1
    • Recurrence rates range from 13-39% depending on treatment 1
    • Local skin reactions are common and expected
  3. Treatment Considerations:

    • Pregnancy status (avoid podofilox, podophyllin, and imiquimod) 3
    • Immunocompromised status (may require more aggressive treatment)
    • Patient preference and compliance ability

Common Pitfalls to Avoid

  1. Overtreatment: Aggressive cryotherapy can lead to scarring or hypopigmentation

  2. Misdiagnosis: Ensure the lesion is truly a wart and not another condition (e.g., seborrheic keratosis, molluscum contagiosum)

  3. Inadequate follow-up: Recurrence is common, especially in the first 3 months after treatment 3

  4. Neglecting patient preferences: Treatment selection should consider the patient's ability to comply with the regimen and their tolerance for pain/discomfort

By following this structured approach, you will demonstrate clinical reasoning and evidence-based decision-making when presenting this case to your attending.

References

Guideline

Wart Treatment Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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