What is the treatment for a stye?

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Last updated: September 29, 2025View editorial policy

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Treatment of Styes

The first-line treatment for a stye (hordeolum) is warm compresses applied to the affected eyelid for 10-15 minutes, 3-4 times daily, combined with gentle eyelid massage and proper eyelid hygiene. 1

Initial Management

First-Line Treatment

  • Warm compresses: Apply for 10-15 minutes, 3-4 times daily
    • This helps to increase blood circulation to the area and promote drainage
    • Use a clean washcloth with warm (not hot) water
  • Gentle massage: After applying warm compresses, gently massage the affected area to encourage drainage
  • Eyelid hygiene: Clean eyelids daily to remove debris and excess oil

Second-Line Treatment

  • Topical antibiotics: If signs of infection are present or there's risk of secondary infection
    • Bacitracin or erythromycin ointment applied to the eyelid margin
    • Apply after warm compresses and cleaning

Third-Line Treatment

  • Combination antibiotic/steroid topical treatment: For moderate to severe cases that don't respond to initial therapy 1

Management of Persistent Styes

For styes that persist beyond 2-4 weeks despite conservative treatment:

  • Fourth-line treatment: Consider intralesional steroid injection or incision and curettage for persistent (>2 months) or large chalazia 1
  • Surgical consultation: Prompt surgical consultation is recommended for aggressive infections with signs of systemic toxicity 2

Prevention of Recurrence

For patients with recurrent styes, consider:

  1. Enhanced eyelid hygiene: More frequent and thorough cleansing

  2. Decolonization strategies:

    • Nasal mupirocin twice daily for 5-10 days
    • Topical antiseptics for 5-14 days
    • Dilute bleach baths (1 teaspoon per gallon of water, 15 minutes twice weekly for 3 months) 1
  3. Additional preventive measures:

    • Complete removal of eye makeup daily
    • Discontinuation of contact lens wear until symptoms resolve
    • Treatment of underlying conditions (e.g., blepharitis)
    • Avoiding sharing personal items like towels and washcloths 1

Special Considerations

  • Monitoring: Reassess after 2-4 weeks to evaluate treatment response 1
  • Referral indications: Refer to an ophthalmologist if there are:
    • Visual changes
    • Corneal involvement
    • Severe eyelid swelling unresponsive to initial treatment
    • Suspected malignancy
    • Cicatricial changes in the conjunctiva 1

Evidence Quality and Caveats

The evidence for stye treatment is primarily based on clinical guidelines rather than high-quality randomized controlled trials. A Cochrane review found no randomized controlled trials specifically for internal hordeolum treatment 3, highlighting a gap in the evidence base.

Some studies have explored alternative treatments such as ear-apex blood-letting, which showed superior pain relief compared to medication alone in one randomized controlled trial 4, 5. However, this approach is not part of standard Western medical practice and requires further validation.

Remember that most styes will resolve spontaneously within 1-2 weeks with conservative treatment. Antibiotics should be used judiciously to prevent antimicrobial resistance, and only when there are clear signs of infection or risk of secondary infection.

References

Guideline

Ocular Infections and Inflammations

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Interventions for acute internal hordeolum.

The Cochrane database of systematic reviews, 2013

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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