What is the best course of treatment for someone experiencing a panic attack?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: September 29, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Management of Panic Attacks

The best course of treatment for someone experiencing an acute panic attack is cognitive-behavioral techniques including controlled breathing exercises, grounding techniques, and reassurance, followed by consideration of medication and longer-term therapy for recurrent episodes. 1

Immediate Management of an Acute Panic Attack

First-Line Interventions

  • Breathing Techniques:

    • Implement diaphragmatic breathing (slow, deep breaths)
    • Guide the person to breathe in for 4 counts, hold for 2, and exhale for 6 counts
    • Avoid hyperventilation which can worsen symptoms 1
  • Grounding Techniques:

    • Sensory grounding: Have the person identify 5 things they can see, 4 things they can touch, 3 things they can hear, 2 things they can smell, and 1 thing they can taste
    • Cognitive distractions such as counting backwards or word games
    • Use of sensory-based distractors (e.g., feeling a textured item) 1
  • Reassurance and Education:

    • Explain that symptoms are not life-threatening
    • Inform that panic attacks typically peak within 10 minutes and then subside
    • Validate their experience while providing realistic reassurance 1

Environmental Modifications

  • Move to a quiet, safe space if possible
  • Reduce environmental stimuli (bright lights, loud noises)
  • Have the person sit or lie down to prevent injury if dizziness occurs 1

Pharmacological Interventions

Acute Management

  • Benzodiazepines may be considered for rapid symptom relief in severe cases:
    • Alprazolam: Starting with 0.25-0.5 mg, can be effective for immediate relief 2
    • Note: While effective for short-term relief, benzodiazepines are not recommended for long-term management due to risk of dependence 3, 2

Long-Term Management for Recurrent Panic Attacks

  • First-line pharmacotherapy: SSRIs

    • Paroxetine (20-60 mg/day): FDA-approved for panic disorder 4, 5
    • Sertraline, fluoxetine, and citalopram are also effective options 5
    • SSRIs typically take 2-4 weeks to show full effect 6
  • Second-line options:

    • SNRIs (e.g., venlafaxine)
    • TCAs (e.g., clomipramine, imipramine)
    • Note: TCAs may be more effective but have more side effects than SSRIs 5

Psychological Interventions

Cognitive-Behavioral Therapy (CBT)

  • Most effective psychological treatment for panic disorder, typically requiring 12-15 sessions 7
  • Key components:
    • Psychoeducation about panic and anxiety
    • Cognitive restructuring to address catastrophic thoughts
    • Interoceptive exposure (controlled exposure to physical sensations)
    • In vivo exposure to feared situations 1, 7

Other Effective Approaches

  • Mindfulness-based techniques: Particularly effective for those with recurring panic attacks
  • Relaxation training: Progressive muscle relaxation can reduce overall anxiety levels
  • Addressing avoidance behaviors: Crucial for preventing development of agoraphobia 8

Follow-Up and Maintenance

When to Seek Professional Help

  • For recurrent panic attacks (more than one episode)
  • When panic attacks significantly impact daily functioning
  • If there's development of avoidance behaviors (potential agoraphobia) 8

Treatment Course

  • Short-term CBT (12-15 sessions) is typically sufficient for significant improvement 7
  • For medication, continue treatment for 6-12 months after symptom resolution
  • Gradual tapering of medication is essential to prevent withdrawal symptoms 2, 4

Special Considerations

Common Pitfalls to Avoid

  • Misdiagnosis: Panic symptoms can mimic cardiac conditions; rule out medical causes when appropriate
  • Over-reliance on medication: Benzodiazepines should not be the sole treatment strategy due to dependence risk 3, 5
  • Reinforcing avoidance: Encouraging avoidance of feared situations can worsen long-term outcomes 8
  • Ignoring comorbidities: Panic disorder often co-occurs with depression and other anxiety disorders 6

Cultural Considerations

  • Symptom presentation may vary across cultures (e.g., somatic vs. cognitive focus)
  • Treatment approaches may need cultural adaptation, as demonstrated in studies with Asian populations 1

By combining immediate management strategies with appropriate long-term interventions, most individuals with panic attacks can achieve significant symptom reduction and improved quality of life.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Treatment of Anxiety and Mood Symptoms

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Pharmacological treatments in panic disorder in adults: a network meta-analysis.

The Cochrane database of systematic reviews, 2023

Research

Current concepts in the treatment of panic disorder.

The Journal of clinical psychiatry, 1999

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.