What ICD-10 (International Classification of Diseases, 10th Revision) codes are used for a patient treated with potassium chloride?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: September 30, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

ICD-10 Codes for Potassium Chloride

The appropriate ICD-10 code for potassium chloride supplementation is E87.6 (Hypokalemia), as this is the primary condition for which potassium chloride is prescribed.

Primary ICD-10 Codes for Potassium Chloride Use

When coding for potassium chloride administration, the following diagnostic codes should be used based on the clinical scenario:

  • E87.6 - Hypokalemia: Primary code for potassium deficiency
  • E87.8 - Other disorders of electrolyte and fluid balance: For mixed electrolyte disorders
  • I50.9 - Heart failure, unspecified: When potassium is given for heart failure management
  • N25.89 - Other disorders resulting from impaired renal tubular function: For renal tubular disorders causing potassium wasting (e.g., Bartter syndrome)

Secondary Codes Based on Underlying Conditions

Additional codes may be required to document the underlying cause of hypokalemia:

  • K59.3 - Megacolon, not elsewhere classified: For potassium loss due to diarrhea
  • T50.3X5A - Adverse effect of electrolytic, caloric, and water-balance agents: For diuretic-induced hypokalemia
  • T43.015A - Adverse effect of tricyclic antidepressants: For medication-induced hypokalemia
  • Z79.899 - Other long term (current) drug therapy: For maintenance potassium supplementation

Coding for Potassium Chloride Administration

For the administration procedure itself:

  • 3E0G7GC - Introduction of Other Therapeutic Substance into Upper GI, Via Natural or Artificial Opening: For oral potassium chloride
  • 3E033GC - Introduction of Other Therapeutic Substance into Peripheral Vein, Percutaneous Approach: For IV potassium chloride

Special Coding Considerations

  1. Severity Coding: For severe hypokalemia with cardiac manifestations, add:

    • I49.8 - Other specified cardiac arrhythmias: For potassium-related arrhythmias
  2. Monitoring Codes:

    • Z51.81 - Encounter for therapeutic drug level monitoring: When checking potassium levels during supplementation
  3. Bartter Syndrome Patients:

    • When coding for potassium chloride use in Bartter syndrome, use N25.89 as the primary code 1
    • Add E87.6 as a secondary code for the hypokalemia

Documentation Requirements

For proper coding, documentation should include:

  1. Serum potassium level (specific value)
  2. Clinical manifestations of hypokalemia, if present
  3. Underlying cause of hypokalemia
  4. Dosage and route of potassium chloride administration
  5. Response to treatment

Common Coding Pitfalls

  • Avoid using E87.5 (Hyperkalemia) when coding for potassium chloride administration
  • Do not use Z79.899 alone without the underlying condition code
  • Remember to code for any adverse effects of potassium chloride (e.g., T50.3X5A for overdose)

Following these guidelines will ensure accurate ICD-10 coding for potassium chloride administration, facilitating proper reimbursement and clinical documentation.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.