Is a calcium level of 10.2 milligrams per deciliter (mg/dL) indicative of hypercalcemia?

From the Guidelines

A calcium level of 10.2 mg/dL is indicative of hypercalcemia, as it exceeds the normal range, according to the k/doqi clinical practice guidelines for bone metabolism and disease in chronic kidney disease 1.

Key Points to Consider

• The normal range for calcium levels is typically considered to be between 8.5-10.2 mg/dL.
• A level of 10.2 mg/dL is considered elevated and may require monitoring and potential treatment, as stated in the guidelines 1.
• Hypercalcemia can be caused by various factors, including laboratory error, dehydration, certain medications, or excessive calcium/vitamin D supplementation.
• Primary hyperparathyroidism and certain cancers can also cause hypercalcemia, but typically present with higher calcium levels.

Recommendations

• If the serum level of corrected total calcium exceeds 10.2 mg/dL, discontinue ergocalciferol therapy and all forms of vitamin D therapy, as recommended by the guidelines 2, 3.
• Monitoring of calcium levels is crucial, and a follow-up blood test in 1-3 months would be appropriate to ensure the level isn't trending upward.
• Increasing water intake and reducing calcium-rich foods temporarily may help if you have a borderline elevated calcium level.
• If symptoms like fatigue, bone pain, kidney stones, or frequent urination are experienced, consult a healthcare provider sooner.

From the Research

Definition of Hypercalcemia

• Hypercalcemia is defined as a serum calcium concentration >10.5 mg/dL 4
• A calcium level of 10.2 mg/dL is below the threshold for hypercalcemia, as defined by a study published in the Medical science monitor 4

Classification of Hypercalcemia

• Hypercalcemia can be classified into mild, moderate, and severe, depending on calcium values 4
• Mild hypercalcemia is typically asymptomatic, while severe hypercalcemia can cause nausea, vomiting, dehydration, confusion, somnolence, and coma 5

Normal Calcium Levels

• The normal range for calcium levels is 8.5 to 10.2 mg/dL, as stated in a case report published in the AACE clinical case reports 6
• A calcium level of 10.2 mg/dL is within the upper limit of the normal range, and therefore not indicative of hypercalcemia 6

Diagnosis and Treatment of Hypercalcemia

• The initial approach to hypercalcemia involves identifying the underlying cause and treating it accordingly 4
• Treatment for hypercalcemia may include hydration, intravenous bisphosphonates, and other medications, depending on the severity and cause of the condition 5, 4