From the Guidelines
Reversatol, also known as Vitamin A, has various topical effects, including potential benefits for skin health, but its specific effects are not directly mentioned in the provided evidence. The provided study 1 discusses the use of topical tazarotene, a derivative of Vitamin A, in the treatment of pediatric psoriasis, highlighting its potential benefits and adverse effects. According to the study 1, tazarotene may be recommended as monotherapy or in combination with topical corticosteroids for the treatment of localized pediatric skin or nail psoriasis, with a strength of recommendation of C and a level of evidence of III. Some key points to consider when using topical tazarotene include:
- Adverse effects are common and include burning, pruritus, and erythema, which are often concentration-related
- Tazarotene may be considered for use on localized, hyperkeratotic lesions
- Tazarotene is teratogenic and should be avoided in pregnant female patients or used with strong caution and only after counseling in adolescents of childbearing potential
- Rotational therapy with topical vitamin D analogues, TCIs, emollients, tar-based therapies, and topical corticosteroids should be considered in children as steroid-sparing regimens to reduce potential adverse effects from overreliance on topical steroid therapy. However, it is essential to note that the provided evidence does not directly discuss the topical effects of Reversatol (Vitamin A), and therefore, the use of Vitamin A topically should be approached with caution and considered on a case-by-case basis, taking into account the potential benefits and risks, as well as the individual patient's needs and medical history.
From the Research
Topical Effects of Reversatol (Vitamin A)
There are no research papers provided that directly discuss the topical effects of Reversatol (Vitamin A) 2, 3, 4, 5, 6.
Available Information on Topical Treatments
- Topical medications are key agents in treating a range of skin conditions, allowing affected areas to be targeted while avoiding systemic side effects 2.
- Topical therapy represents the fundamental treatment modality for psoriasis, with various agents being used to manage the condition 3.
- Other topical agents, such as 2-dimethylaminoethanol (DMAE), have been shown to be safe and efficacious in mitigating forehead lines and periorbital fine wrinkles, and improving lip shape and fullness and the overall appearance of aging skin 4.
- Topical hydroquinone (HQ) has been used to treat disorders of hyperpigmentation, although its use is not without side effects and is currently not approved for over-the-counter use in the United States 5.
- Rutin-loaded ethosomes have been investigated for their safety and antioxidant efficacy profiles for topical application, with results showing a relevant bioactive compound loading and antioxidant in vitro activity 6.