What is the recommended dose of acetaminophen (paracetamol) for a 14-year-old?

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Acetaminophen Dosing for a 14-Year-Old

For a 14-year-old, the recommended dose of acetaminophen is 10-15 mg/kg every 6 hours, with a maximum daily dose of 60 mg/kg/day not to exceed 4 grams per day. 1

Dosing Guidelines

Weight-Based Dosing (Preferred Method)

  • Calculate dose based on 10-15 mg/kg per dose
  • Administer every 6 hours as needed
  • Maximum of 4 doses in 24 hours
  • Do not exceed 60 mg/kg/day or 4 grams total daily dose, whichever is less

Standard Dosing (If Weight Unknown)

  • For most 14-year-olds (who typically weigh 40-70 kg):
    • 500-650 mg per dose
    • Every 6 hours as needed
    • Maximum 4 doses in 24 hours
    • Not to exceed 4 grams total daily dose

Important Considerations

Safety Profile

  • Acetaminophen is generally well-tolerated when used at recommended doses 2
  • It remains the first-line choice for treatment of both fever and pain in pediatric patients
  • Unlike NSAIDs, acetaminophen is not associated with significant gastrointestinal bleeding or cardiovascular toxicity 1

Monitoring and Precautions

  • Parents should be educated on the maximum safe dose (60 mg/kg/day not exceeding 4 g/24 hours) from all sources 2
  • Careful recording of dose times is essential to avoid accidentally exceeding the maximum recommended dose 3
  • Hepatotoxicity can occur with overdose; single ingestions of more than ten times the recommended dose are potentially toxic 2

Common Pitfalls to Avoid

  1. Dosing confusion: Some parents may be confused by different dosing recommendations on various acetaminophen products. Always clarify the concentration of the product being used 4

  2. Concurrent use in combination products: Many over-the-counter cold medicines and prescription pain medications contain acetaminophen. Ensure the total daily dose from all sources doesn't exceed the maximum 2

  3. Inadequate dosing: Some dosing schedules recommend inadequate amounts of acetaminophen. Weight-based dosing (10-15 mg/kg) ensures accurate therapeutic levels 5

  4. Extended use: For acute pain or fever, acetaminophen should be used for the shortest duration necessary. Prolonged use increases risk of adverse effects 1

By following these guidelines, acetaminophen can be safely and effectively used to manage pain and fever in a 14-year-old patient.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Paracetamol efficacy and safety in children: the first 40 years.

American journal of therapeutics, 2000

Research

Pediatric dosing of acetaminophen.

Pediatric pharmacology (New York, N.Y.), 1983

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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