Treatment of Bell's Palsy
Oral corticosteroids are strongly recommended as first-line treatment for Bell's palsy, with prednisolone 50-60 mg daily for 5 days followed by a 5-day taper showing significantly improved recovery rates. 1
Pharmacological Management
Corticosteroid Therapy
- Prednisolone should be initiated within 72 hours of symptom onset 1, 2
- Dosing regimen:
- Treatment with prednisolone significantly improves complete recovery rates:
- Number needed to treat (NNT) for one additional complete recovery: 6 patients 5
Antiviral Therapy
- Antiviral therapy alone is ineffective and not recommended 1, 3
- There is minimal additional benefit when antivirals are combined with steroids 1
- Studies show no significant difference in recovery rates between acyclovir and no acyclovir groups (71.2% vs 75.7% at 3 months) 2
- If antivirals are considered as adjunctive therapy, options include:
Eye Protection Measures
- Critical for patients with impaired eye closure to prevent corneal damage 1
- Recommended measures include:
- Artificial tears during daytime
- Lubricating ointment at night
- Taping eyelids closed if necessary for complete protection
Rehabilitation Considerations
- Physical therapy may benefit patients with more severe paralysis 3
- For persistent symptoms beyond 3 months:
Prognosis
- Without treatment, over two-thirds of patients experience complete spontaneous recovery 3
- With early prednisolone treatment, recovery rates increase to 83% at 3 months and 94.4% at 9 months 2
- Children and pregnant women have higher spontaneous recovery rates (up to 90%) 3
Clinical Pearls and Pitfalls
- Key Pitfall: Delaying corticosteroid treatment beyond 72 hours may reduce effectiveness
- Important Consideration: Laboratory testing and imaging are not required for typical Bell's palsy diagnosis 3
- Caution: Ensure that facial weakness is truly Bell's palsy (idiopathic) and not due to other causes that would require different management
- Special Populations: Elderly patients may particularly benefit from combined treatment with corticosteroids and antivirals, with one study showing 100% recovery in treated patients over 60 years compared to only 42% in untreated controls 6