Treatment of Severe Poison Ivy in Children
For severe poison ivy dermatitis in children, a combination of prescription-strength topical corticosteroids and systemic corticosteroids is recommended to reduce symptom duration and severity. 1
Immediate Management
- Decontamination: Wash affected areas with soap and water as soon as possible after exposure
- Effectiveness decreases rapidly with time: 100% effective immediately, 50% at 10 minutes, 25% at 15 minutes 1
- Even washing 2 hours after exposure can reduce symptoms by 55-70%
Treatment Algorithm Based on Severity
Mild to Moderate Cases
Topical Corticosteroids:
- First-line: Prescription-strength topical corticosteroids 1
- For body: Class I topical corticosteroids (clobetasol propionate, halobetasol propionate)
- For face: Class V/VI corticosteroids (desonide, hydrocortisone 2.5%)
- OTC options: Hydrocortisone (for children ≥2 years) applied to affected area no more than 3-4 times daily 2
- Note: OTC hydrocortisone has limited effectiveness for poison ivy 1
- First-line: Prescription-strength topical corticosteroids 1
Symptomatic Relief:
- Cool compresses to affected areas
- Oatmeal baths for widespread rash
Antihistamines (primarily for sleep disruption from itching):
- Cetirizine/loratadine 10 mg daily (age-appropriate dosing)
- Hydroxyzine 10-25 mg at bedtime (for severe itching disrupting sleep) 1
Severe Cases
Severe cases are characterized by extensive rash, facial/genital involvement, or significant discomfort:
Systemic Corticosteroids:
Continue Topical Therapy:
- High-potency topical corticosteroids to affected areas
- Combination of systemic and topical corticosteroids reduces itching duration 1
Special Considerations for Children
- Avoid long-term use of high-potency topical steroids, especially on the face, genitals, and skin folds
- Monitor for side effects of systemic corticosteroids, including mood changes, increased appetite, and sleep disturbances
- For children under 2 years, consult a physician before using any topical hydrocortisone 2
Monitoring and Follow-up
- Improvement should begin within 1-3 days of treatment
- Complete healing typically occurs within 1-3 weeks 5
- Watch for signs of secondary bacterial infection (increased redness, warmth, swelling, pus, fever)
- If infection is suspected, appropriate antibiotics should be administered for at least 14 days 1
Prevention Education
- Teach children to recognize and avoid poison ivy plants ("leaves of three, let them be")
- Recommend protective clothing when in wooded areas
- Wash all clothing, pets, and tools that may have contacted the plant
When to Refer to Emergency Care
- Extensive rash covering large body areas
- Severe facial or genital involvement
- Difficulty breathing or swallowing
- Signs of systemic involvement
The evidence strongly supports longer courses (14+ days) of systemic corticosteroids for severe poison ivy dermatitis to reduce healthcare utilization and prevent symptom recurrence 4, 3.