Differential Diagnosis for Proximal Metacarpal Number One Bilateral Pain and Burning Sensation
Single Most Likely Diagnosis
- Carpal Tunnel Syndrome: This condition is the most likely cause due to its common presentation of pain and burning sensation in the hand, particularly affecting the thumb (proximal metacarpal number one), and its bilateral occurrence is not uncommon, especially in individuals with repetitive strain injuries or certain underlying health conditions.
Other Likely Diagnoses
- De Quervain's Tenosynovitis: This condition affects the tendons on the thumb side of your wrist and can cause pain and tenderness, especially when forming a fist, grasping, or turning the wrist. It's a common cause of thumb pain and could radiate to the proximal metacarpal area.
- Trigger Thumb: Characterized by pain and stiffness in the thumb, trigger thumb can cause discomfort in the proximal metacarpal area due to the inflammation of the tendon sheath.
- Arthritis (Osteoarthritis or Rheumatoid Arthritis): Both forms of arthritis can affect the joints of the hand, including the base of the thumb, leading to pain and burning sensations.
Do Not Miss Diagnoses
- Ganglion Cyst: Although not typically deadly, a ganglion cyst near the wrist or the base of the thumb can cause significant pain and discomfort. It's crucial to diagnose and treat to prevent nerve damage or other complications.
- Infection (e.g., Cellulitis or Abscess): Infections in the hand can quickly become serious, leading to severe consequences if not promptly treated. Symptoms can include pain, redness, swelling, and warmth.
- Neoplastic Conditions: Tumors, whether benign or malignant, can cause pain and other symptoms in the hand. Early detection is critical for effective treatment.
Rare Diagnoses
- Complex Regional Pain Syndrome (CRPS): A rare condition characterized by intense burning or aching pain in the hands or feet after an injury or trauma. It's rare but should be considered in cases of unexplained, severe pain.
- Raynaud’s Phenomenon: This condition affects blood flow to the fingers and toes, and sometimes the ears, nose, and lips, causing them to turn blue or white in response to cold or stress. It could potentially cause burning sensations in the hands, including the thumb area.
- Sarcoidosis: A rare disease characterized by the growth of granulomas (inflammatory cells) in any part of the body, including the hands. It could cause pain and swelling in the affected areas.