What is the differential diagnosis for a 75-year-old female presenting with right lower quadrant (RLQ) abdominal pain and pruritus (itching) for 2 weeks following a blood draw?

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Differential Diagnosis for 75-year-old Female with Right Abdominal Pain and Itchiness after Blood Draw

  • Single Most Likely Diagnosis
    • Cholecystitis: The presentation of right upper quadrant abdominal pain, especially after a procedure that may cause gallbladder contraction like a blood draw, suggests cholecystitis, which is inflammation of the gallbladder, often due to gallstones.
  • Other Likely Diagnoses
    • Biliary Colic: Pain from gallstones that have not yet caused an infection, which could be precipitated by the gallbladder contracting after a blood draw.
    • Hepatitis: Could be a cause of both abdominal pain and itchiness, especially if the blood draw was contaminated or if the patient has a pre-existing liver condition.
    • Pancreatitis: Inflammation of the pancreas, which could cause abdominal pain and potentially itchiness if there's an associated liver or biliary issue.
  • Do Not Miss Diagnoses
    • Liver or Bile Duct Cancer: Although less likely, these conditions can present with similar symptoms and would have a significant impact on prognosis if missed.
    • Sphincter of Oddi Dysfunction: A condition that affects the sphincter controlling the flow of bile and pancreatic juices, which could cause recurrent biliary-type pain.
    • Hemolytic Disease (e.g., Hemolytic Anemia): If the blood draw was complicated or if there's an underlying condition affecting red blood cells, this could lead to jaundice and itchiness.
  • Rare Diagnoses
    • Zollinger-Ellison Syndrome: A rare disorder characterized by excessive gastric acid production leading to peptic ulcers, which could cause abdominal pain.
    • Porphyria: A group of disorders that can cause abdominal pain and neurological symptoms, including itchiness, though this is less common.
    • Intra-abdominal Lymphoma: A rare cause of abdominal pain and could potentially cause itchiness if there's liver involvement or systemic symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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