From the Research
Interaction between Ashwagandha and Levothyroxine
- The interaction between Ashwagandha and Levothyroxine (thyroxine, T4) is a topic of interest due to the potential effects of Ashwagandha on thyroid function 1, 2, 3, 4.
- Studies have shown that Ashwagandha may increase thyroxine levels, which could potentially interact with Levothyroxine treatment 2, 3, 4.
- A study published in 2018 found that Ashwagandha root extract improved serum TSH, T3, and T4 levels in subclinical hypothyroid patients, suggesting a potential benefit for normalizing thyroid indices 3.
- Another study published in 2023 found that Ashwagandha treatment increased T3 and T4 levels, and decreased TSH levels, in patients with hypothyroidism 4.
- However, a case report published in 2022 highlighted the potential risk of thyrotoxicosis associated with Ashwagandha use, particularly in patients with a history of hypothyroidism 5.
Safety and Efficacy Considerations
- The safety and efficacy of taking Ashwagandha with Levothyroxine require careful consideration, as the interaction between the two substances is not fully understood 1, 2, 3, 4, 5.
- Patients taking Levothyroxine should consult with their healthcare provider before using Ashwagandha, as the potential effects on thyroid function and the risk of thyrotoxicosis need to be carefully monitored 5.
- Further research is needed to fully understand the interaction between Ashwagandha and Levothyroxine, and to determine the safe and effective use of Ashwagandha in patients with hypothyroidism 1, 2, 3, 4.