What is the role of Desmopressin (DDAVP) in vestibular disorders?

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From the Research

Desmopressin (DDAVP) in Vestibular Disorders

There are no research papers to assist in answering this question, as the provided studies focus on the use of desmopressin in bleeding disorders, hemophilia, and von Willebrand disease, with no mention of its role in vestibular disorders.

Alternative Uses of Desmopressin

Some studies suggest that desmopressin may have potential uses beyond bleeding disorders, including:

  • Renal colic and bleeding control 1
  • Central nervous system and oncology 1
  • Nocturnal polyuria, diabetes insipidus, and uremic bleeding 2
  • Management of intracranial bleed and trauma resuscitation with active hemorrhage 2

Mechanism of Action

Desmopressin works by:

  • Stimulating the release of factor VIII and von Willebrand factor from storage sites 2
  • Facilitating platelet-vessel wall adhesion, resulting in a substantial hemostatic effect 2
  • Increasing the plasma levels of factor VIII and von Willebrand factor 3, 4, 5

References

Research

Role of Desmopressin in Bleeding Disorders: What Indian Physicians Need to Know?

The Journal of the Association of Physicians of India, 2025

Research

The use of desmopressin in open-heart surgery.

Haemophilia : the official journal of the World Federation of Hemophilia, 2008

Research

Desmopressin (DDAVP) for treatment of disorders of hemostasis.

Progress in hemostasis and thrombosis, 1986

Research

Desmopressin: a nontransfusional hemostatic agent.

Annual review of medicine, 1990

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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