Preoperative Preparation and Surgical Techniques for Mitral Valve Repair
Thorough preoperative evaluation with transesophageal echocardiography (TEE) is essential for successful mitral valve repair, with patient selection focusing on valve morphology, ventricular function, and anatomical considerations to determine repair feasibility and approach. 1
Patient Selection and Preoperative Evaluation
Echocardiographic Assessment
- Transthoracic echocardiography (TTE) is the preferred initial imaging technique for diagnosis and severity assessment of mitral valve disease 1
- Transesophageal echocardiography (TEE) is crucial for:
- Evaluating presence and severity of concurrent mitral regurgitation
- Clarifying severity and mechanism of valve lesions
- Determining appropriateness for valve repair over replacement
- Obtaining detailed information on mitral anatomy before intervention 1
- 3D TEE provides greater accuracy of measurement of mitral valve area 1
Ideal Candidates for Initial Mitral Valve Repair
- Patients requiring simple annuloplasty
- Focal posterior leaflet prolapse
- Mitral valve replacement candidates without complex pathology 1
Relative Contraindications for Minimally Invasive Approach
- Significant mitral annular calcification requiring extensive debridement
- Extremely complex repairs (e.g., rheumatic disease)
- Left ventricular ejection fraction <25%
- Severe right ventricular dysfunction
- Pulmonary artery pressure >70 mm Hg
- Significant aortic regurgitation (more than mild)
- Kyphoscoliosis and pectus excavatum 1
Additional Preoperative Testing
- Computed tomography angiography (CTA) to evaluate:
- Ascending aortic disease
- Vascular access for cannulation
- Anatomical considerations 1
- Coronary angiography for:
- Men >40 years
- Post-menopausal women
- Patients with cardiovascular risk factors or history of coronary artery disease 1
Surgical Techniques for Mitral Valve Repair
Fundamental Principles
- Total removal of infected/damaged tissues
- Reconstruction of cardiac morphology
- Valve repair whenever possible, particularly for mitral valve 1
Specific Repair Techniques
Simple lesions:
- Perforations in valve cusps/leaflets: repair with untreated or glutaraldehyde-treated autologous or bovine pericardial patch
- Isolated/multiple ruptured chordae: replacement with polytetrafluoroethylene neo-chordae 1
Complex lesions:
- Extensive destruction of single leaflet or abscess presence may still be repairable
- Intraoperative assessment after debridement is crucial to evaluate tissue quality
- Pericardial patches, tricuspid autografts, or flipped-over mitral patches may be used 1
Repair vs. Replacement Decision-Making
Mitral valve repair is strongly preferred over replacement when:
Consider replacement in patients with:
- Unfavorable morphological characteristics
- Significant mitral annular calcification
- Rheumatic valve disease requiring complex repair 1
Surgical Approach Options
- Traditional sternotomy
- Minimally invasive approaches:
- Right mini-thoracotomy
- Port-access techniques
- Robotic-assisted surgery 1
Perioperative Considerations
Anesthesia and Monitoring
- Intraoperative TEE is essential to:
- Determine exact location and extent of pathology
- Guide surgery
- Assess repair results
- Help in early postoperative follow-up 1
Myocardial Protection
- For minimally invasive approaches:
- Consider lower systemic perfusate temperatures
- More frequent redosing of cardioplegia
- Optimal venous drainage is crucial, especially in patients with RV dysfunction 1
Postoperative Management
- Careful anticoagulation management for patients with mechanical valves
- Consider intravenous heparin or subcutaneous low-molecular-weight heparin to cover periods of subtherapeutic anticoagulation in high-risk patients 1
Importance of Surgical Expertise
- Outcomes of mitral valve repair are highly dependent on surgeon experience and center volume 1, 2
- High-volume centers can achieve repair rates approaching 100% for degenerative mitral valve disease 3
- Referral to a Heart Valve Center of Excellence is recommended when complex repair is anticipated 2
Common Pitfalls and Caveats
- Underestimating the complexity of repair in cases with significant annular calcification
- Inadequate preoperative imaging leading to unexpected findings during surgery
- Failure to recognize unfavorable valve morphology preoperatively
- Attempting complex repairs without adequate surgical expertise
- Not considering the patient's comorbidities and operative risk in decision-making 1
By following these guidelines and principles, successful mitral valve repair can be achieved in the majority of patients, leading to better long-term outcomes compared to valve replacement.