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Differential Diagnosis for Swollen Eyelid

The following is a list of potential diagnoses for a swollen eyelid, categorized by likelihood and potential impact.

  • Single Most Likely Diagnosis
    • Blepharitis: This is an inflammation of the eyelids that can cause swelling, redness, and itching. It's a common condition and often related to poor eyelid hygiene, Demodex mites, or rosacea.
  • Other Likely Diagnoses
    • Conjunctivitis (Pink Eye): An infection or inflammation of the outer membrane of the eyeball and the inner eyelid. It can be viral, bacterial, or allergic, leading to swelling, redness, and discharge.
    • Hordeolum (Stye): A localized infection or inflammation of the eyelid margin involving hair follicles of the eyelashes or meibomian glands. It presents as a painful, swollen nodule on the eyelid.
    • Chalazion: A small bump on the eyelid due to a blocked oil gland. It can cause swelling and may become inflamed or infected.
    • Allergic Reaction: Allergies to makeup, contact lens solution, or other substances can cause eyelid swelling, redness, and itching.
  • Do Not Miss Diagnoses
    • Orbital Cellulitis: A serious infection of the tissues surrounding the eye, which can lead to severe complications if not promptly treated. Symptoms include swelling, redness, pain, and decreased eye movement.
    • Angioedema: A condition characterized by rapid swelling of the dermis, subcutaneous tissue, mucosa, and submucosal tissues. It can be life-threatening if it involves the airway.
    • Herpes Zoster (Shingles): When it affects the eye, it's known as herpes zoster ophthalmicus. It can cause severe pain, swelling, and potentially lead to complications like vision loss if not treated.
  • Rare Diagnoses
    • Graves' Disease: An autoimmune disorder that can cause bulging eyes (exophthalmos) and eyelid swelling among other symptoms.
    • Sarcoidosis: A condition that can affect various parts of the body, including the eyes, leading to uveitis, conjunctivitis, and eyelid swelling.
    • Wegener's Granulomatosis (Granulomatosis with Polyangiitis): A rare autoimmune disorder that can affect the eyes, among other areas, causing inflammation and damage.

Each of these diagnoses has distinct features and potential consequences, emphasizing the importance of a thorough evaluation to determine the underlying cause of a swollen eyelid.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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