Treatment Guidelines for Chalazion
First-Line Management
The first-line treatment for chalazion is warm compresses and eyelid hygiene, which should be initiated promptly upon diagnosis. 1
Warm Compress Application
- Apply warm compresses to affected eyelid for several minutes, 1-2 times daily
- Options for warm compresses include:
- Clean washcloth with hot tap water
- Commercial heat pack
- Homemade bean/rice bag heated in microwave
- The Re-Heater or hard-boiled egg (both show excellent heat retention) 2
- Important: Ensure temperature is comfortable to avoid skin burns
Eyelid Hygiene
- Gently cleanse eyelid margins to remove crusting
- Use diluted baby shampoo or commercial eyelid cleaner on a cotton ball/swab
- Hypochlorous acid 0.01% cleaners have strong antimicrobial effects 1
Second-Line Treatments
If conservative management fails after 4-6 weeks, consider:
Intralesional Steroid Injection
- Triamcinolone acetonide injection (0.2 mL of 10 mg/mL)
- Resolution rate of approximately 84% 3
- Advantages: Less painful and less inconvenient than surgical options
- Patient satisfaction comparable to surgical intervention 3
Incision and Curettage
- Surgical removal of the chalazion
- Resolution rate of approximately 87% 3
- More painful than steroid injection but highly effective 3
- Consider for larger or persistent chalazia
Special Considerations
Pediatric Patients
- Conservative treatment remains first-line in children
- Consider underlying conditions that may contribute to chalazion formation:
- Vitamin A deficiency
- Demodex infestation
- Rosacea 4
Warning Signs Requiring Referral
- Recurrent chalazia in the same location
- Marked asymmetry of the lesion
- Resistance to therapy
- These may indicate sebaceous carcinoma, especially in elderly patients 1, 5
- Biopsy is indicated in these cases 1
Additional Considerations
- Antibiotic ointment (bacitracin or erythromycin) can be applied to eyelid margins 1+ times daily for a few weeks as needed 1
- Avoid aggressive eyelid manipulation in patients with advanced glaucoma or filtering procedures 1
- Children with recurrent chalazia may have unrecognized chronic blepharokeratoconjunctivitis requiring more aggressive treatment 1
Treatment Algorithm
- Initial 4-6 weeks: Warm compresses + eyelid hygiene
- If no improvement: Proceed to either:
- Intralesional steroid injection (less painful, equally effective)
- Incision and curettage (slightly more effective but more painful)
- If recurrent or atypical: Refer to ophthalmologist for biopsy to rule out malignancy
Common Pitfalls
- Failing to recognize that untreated hordeola can progress to chalazia
- Using compresses that are too hot, risking skin burns
- Missing underlying sebaceous carcinoma in recurrent cases, especially in elderly patients
- Inadequate duration of conservative treatment before moving to invasive options