What is the recommended dose of Tylenol (acetaminophen) for a 2-month-old infant weighing 5.4 kg, given an 80 mg/ml concentration?

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Tylenol (Acetaminophen) Dosing for a 2-Month-Old Infant

For a 2-month-old infant weighing 5.4 kg with an 80 mg/ml concentration of Tylenol (acetaminophen), the recommended dose is 16.2 mg (0.2 ml) given every 6 hours as needed.

Dosage Calculation

The appropriate acetaminophen dosing for infants is based on weight:

  • Standard pediatric acetaminophen dose: 10-15 mg/kg/dose every 4-6 hours as needed
  • For this 5.4 kg infant:
    • Minimum dose (10 mg/kg): 5.4 kg × 10 mg/kg = 54 mg
    • Maximum dose (15 mg/kg): 5.4 kg × 15 mg/kg = 81 mg
    • Recommended dose (using 15 mg/kg): 5.4 kg × 15 mg/kg = 81 mg

Given the 80 mg/ml concentration:

  • Volume to administer = 81 mg ÷ 80 mg/ml = 1.01 ml
  • For practical administration, this can be rounded to 1 ml (80 mg)

Administration Guidelines

  • Use the appropriate measuring device (oral syringe) for accurate dosing
  • Maximum frequency: Every 4-6 hours as needed
  • Maximum daily doses: No more than 5 doses in 24 hours
  • Duration: For fever or pain, use for no more than 3 days without consulting a healthcare provider

Important Considerations

  • Acetaminophen should be used cautiously in neonates and young infants due to their immature hepatic metabolism
  • Avoid concurrent administration of other medications containing acetaminophen to prevent overdose
  • Monitor for signs of efficacy (reduction in fever, improved comfort) and any adverse effects

Safety Precautions

  • Double-check the concentration before administration (80 mg/ml is the infant formulation)
  • Store medication safely out of reach of children
  • Record all doses given to avoid accidental overdosing
  • Contact healthcare provider if fever persists beyond 3 days or if the infant's condition worsens

Remember that acetaminophen overdose can cause serious hepatotoxicity, so accurate dosing and administration are critical for safe use in infants.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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