Treatment of Blood Blisters
For blood blisters, the optimal treatment is to drain the blister by piercing it at the base with a sterile needle while keeping the blister roof intact as a biological dressing, then apply a non-adherent occlusive dressing to promote wound healing. 1
Initial Management
Draining the blister:
- Use a sterile needle to pierce the blister at its base
- Keep the blister roof intact as it serves as a natural protective dressing 2, 1
- Leave small to medium blisters intact if they're not causing discomfort 2
- Only drain larger blisters that are painful or interfere with function (such as on the sole of the foot) 2
After draining:
When to Remove the Blister Roof
- Only remove the blister roof if:
Infection Prevention
Monitor for signs of infection:
- Increasing redness, warmth, pain
- Presence of pus
- Red streaks extending from the blister 1
If infection develops:
- Seek medical attention
- Oral antibiotics may be necessary (options include Dicloxacillin, Cephalexin, Clindamycin, or Amoxicillin/clavulanate) 1
Additional Care Measures
For painful blisters:
- Consider over-the-counter pain relievers like acetaminophen or NSAIDs 1
- Avoid home remedies that might introduce infection
For extensive areas of erosion:
Prevention of Future Blood Blisters
- Choose properly fitted footwear with a rounded toe box and flexible sole 1
- Wear moisture-wicking socks 1
- Use cornflour on areas prone to blisters to control moisture and reduce friction 1
- Protect "hot spots" with protective padding or tape 1
- Recent exposure to repeated low-intensity friction forces can lead to epidermal thickening, which may reduce blister likelihood 3
Special Considerations
- Ensure tetanus immunization is up-to-date for traumatic blisters 1
- Seek urgent medical attention if:
- The blister is large (>30% body surface area)
- It involves mucous membranes
- There are signs of systemic illness 1
Common Pitfalls to Avoid
- Do not apply ice or ice water to blisters as this can increase tissue damage 2
- Avoid rupturing the blister in a non-sterile manner, which increases infection risk
- Don't remove the blister roof unnecessarily as it serves as a natural protective barrier 2
- Avoid using adhesive bandages directly on the blister as they can cause further damage when removed
By following these evidence-based guidelines, most blood blisters will heal without complications within a few days to a week, with proper protection and care being the cornerstones of management.