Is Vicryl (polyglactin 910) an absorbable suture?

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Vicryl (Polyglactin 910) is an Absorbable Suture

Yes, Vicryl (polyglactin 910) is definitively an absorbable suture material. 1, 2

Characteristics of Vicryl as an Absorbable Suture

Vicryl is a synthetic absorbable suture made from polyglactin 910, which has the following properties:

  • Structure: Available as a braided (multifilament) construction 3
  • Composition: Made from 90:10 poly(glycolide-co-L(-)-lactide) 3
  • Absorption profile: Slowly absorbable, which is preferred over rapidly absorbable sutures for wound closure 4
  • Variants: Also available as Vicryl Rapide, which is a rapidly dissolving synthetic suture 1

Clinical Properties and Performance

Vicryl demonstrates several important clinical characteristics:

  • Tensile strength: High tensile strength comparable to or superior to other synthetic non-absorbable suture materials 2
  • Tissue reaction: No unfavorable wound reaction has been registered 2
  • Absorption: Complete absorption occurs over time
  • Handling: When coated, Vicryl has improved handling properties, making passage through tissue easier 5

Comparison with Other Absorbable Sutures

Vicryl is one of several absorbable suture options:

  • Other absorbable multifilament options:

    • Dexon (polyglycolic acid) 1, 3
  • Absorbable monofilament options:

    • Monocryl (poliglecaprone 25) 1, 3
    • PDS II (p-dioxanone homopolymer) 3
    • Maxon (polyglyconate) 1, 3

Clinical Applications

According to current guidelines, Vicryl is commonly used in:

  • Perineal laceration repairs, particularly second-degree lacerations 1
  • General surgery applications 2
  • Ophthalmologic procedures 6
  • Aesthetic plastic surgery 7

Important Considerations

  • Suture selection: When choosing between absorbable suture materials, slowly absorbable sutures (like standard Vicryl) are generally preferred over rapidly absorbable ones for wound closure 1, 4
  • Monofilament vs. multifilament: While Vicryl is a multifilament (braided) suture, monofilament sutures may be preferred in some situations as they cause less bacterial seeding and may be less likely to cause infection 1
  • Coated vs. uncoated: Coated Vicryl sutures have improved handling properties and ease of passage through tissue 5

Potential Pitfalls

  • Braided sutures like Vicryl may have concerns related to tissue drag and potential for infection through the interstices of the braid structure 3
  • Standard synthetic sutures like Vicryl may occasionally require removal of unabsorbed suture material 1
  • Rapidly absorbing variants (Vicryl Rapide) may be preferred in certain situations despite higher cost due to lower need for postpartum suture removal 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Experiences with polyglactin 910 (Vicryl) in general surgery.

Acta chirurgica Scandinavica, 1977

Guideline

Knot Security for Absorbable Sutures

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Coated Vicryl synthetic absorbable sutures.

Surgery, gynecology & obstetrics, 1980

Research

Vicryl (polyglactin 910) in cataract surgery. A controlled trial.

The British journal of ophthalmology, 1976

Research

Vicryl sutures.

Aesthetic plastic surgery, 1976

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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