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Differential Diagnosis for Hair Loss in Females

Single Most Likely Diagnosis

  • Androgenetic Alopecia (Female Pattern Hair Loss): This is the most common cause of hair loss in females, accounting for approximately 40% of cases. It is characterized by a gradual thinning of hair, particularly on the top and crown of the scalp, due to the sensitivity of hair follicles to androgens.

Other Likely Diagnoses

  • Telogen Effluvium: A condition that causes excessive hair shedding due to a disruption in the normal hair growth cycle, often triggered by stress, hormonal changes, or medical conditions.
  • Alopecia Areata: An autoimmune condition that leads to patchy hair loss, which can be localized or widespread.
  • Thyroid Disorders: Both hypothyroidism and hyperthyroidism can cause hair loss due to the metabolic effects on hair growth.
  • Nutritional Deficiencies: Deficiencies in iron, zinc, biotin, or vitamin D can contribute to hair loss.

Do Not Miss Diagnoses

  • Systemic Lupus Erythematosus (SLE): A chronic autoimmune disease that can cause hair loss, among other systemic symptoms. Early diagnosis is crucial due to the potential for severe organ damage.
  • Thyroid Cancer: Although rare, thyroid cancer can cause hair loss, and early detection is vital for effective treatment.
  • Pituitary Tumors: Tumors affecting the pituitary gland can disrupt hormone production, leading to hair loss, among other symptoms.

Rare Diagnoses

  • Trichotillomania: A psychological disorder characterized by compulsive hair pulling, leading to noticeable hair loss.
  • Traction Alopecia: Hair loss caused by constant pulling on the hair, such as from tight hairstyles.
  • Frontal Fibrosing Alopecia: A rare condition characterized by hair loss and scarring on the scalp, particularly affecting the frontal area.
  • Lichen Planopilaris: An inflammatory condition that causes hair loss, often accompanied by skin and mucous membrane lesions.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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