Differential Diagnosis for Hair Loss in Females
Single Most Likely Diagnosis
- Androgenetic Alopecia (Female Pattern Hair Loss): This is the most common cause of hair loss in females, accounting for approximately 40% of cases. It is characterized by a gradual thinning of hair, particularly on the top and crown of the scalp, due to the sensitivity of hair follicles to androgens.
Other Likely Diagnoses
- Telogen Effluvium: A condition that causes excessive hair shedding due to a disruption in the normal hair growth cycle, often triggered by stress, hormonal changes, or medical conditions.
- Alopecia Areata: An autoimmune condition that leads to patchy hair loss, which can be localized or widespread.
- Thyroid Disorders: Both hypothyroidism and hyperthyroidism can cause hair loss due to the metabolic effects on hair growth.
- Nutritional Deficiencies: Deficiencies in iron, zinc, biotin, or vitamin D can contribute to hair loss.
Do Not Miss Diagnoses
- Systemic Lupus Erythematosus (SLE): A chronic autoimmune disease that can cause hair loss, among other systemic symptoms. Early diagnosis is crucial due to the potential for severe organ damage.
- Thyroid Cancer: Although rare, thyroid cancer can cause hair loss, and early detection is vital for effective treatment.
- Pituitary Tumors: Tumors affecting the pituitary gland can disrupt hormone production, leading to hair loss, among other symptoms.
Rare Diagnoses
- Trichotillomania: A psychological disorder characterized by compulsive hair pulling, leading to noticeable hair loss.
- Traction Alopecia: Hair loss caused by constant pulling on the hair, such as from tight hairstyles.
- Frontal Fibrosing Alopecia: A rare condition characterized by hair loss and scarring on the scalp, particularly affecting the frontal area.
- Lichen Planopilaris: An inflammatory condition that causes hair loss, often accompanied by skin and mucous membrane lesions.