Comprehensive Cardiac and Peripheral Vascular Assessment
A thorough cardiac and peripheral vascular assessment requires systematic evaluation of cardiac anatomy, heart sounds, murmurs, pulses, and vascular sufficiency to accurately identify cardiovascular pathology and guide clinical decision-making.
Normal Cardiac Anatomy and Examination
Cardiac Anatomy
- Atria: Right atrium receives deoxygenated blood from systemic circulation; left atrium receives oxygenated blood from pulmonary veins
- Ventricles: Right ventricle pumps blood to lungs; left ventricle pumps blood to systemic circulation
- Valves:
- Atrioventricular: Tricuspid (right), Mitral (left)
- Semilunar: Pulmonic (right), Aortic (left)
- Blood flow: Right atrium → tricuspid valve → right ventricle → pulmonic valve → pulmonary arteries → lungs → pulmonary veins → left atrium → mitral valve → left ventricle → aortic valve → aorta → systemic circulation
Normal Cardiac Examination
- Inspection: Observe for visible pulsations, heaves, or abnormal movements
- Palpation: Assess Point of Maximal Impulse (PMI)
- Normally located at 5th intercostal space, midclavicular line
- Displaced PMI suggests cardiomegaly, LV hypertrophy, or volume overload 1
- Assess for thrills (palpable vibrations associated with loud murmurs)
- Percussion: Limited utility in modern practice
- Auscultation: Systematic approach
- Aortic area: 2nd right intercostal space
- Pulmonic area: 2nd left intercostal space
- Tricuspid area: Left lower sternal border
- Mitral area: 5th intercostal space, midclavicular line
- Listen for S1, S2, abnormal S3/S4, and murmurs
Heart Sounds
- S1: Represents closure of mitral and tricuspid valves at beginning of systole
- S2: Represents closure of aortic and pulmonic valves at end of systole
- S3: Early diastolic sound; pathological in adults, suggests volume overload or heart failure
- S4: Late diastolic sound; suggests decreased ventricular compliance or increased atrial contraction
Cardiac Murmurs
Systolic Murmurs
- Aortic stenosis: Harsh, crescendo-decrescendo systolic murmur, best heard at right upper sternal border, radiates to carotids
- Mitral regurgitation: Holosystolic murmur, best heard at apex, radiates to axilla
Diastolic Murmurs
- Aortic regurgitation: High-pitched, decrescendo diastolic murmur, best heard at left sternal border
- Mitral stenosis: Low-pitched, rumbling diastolic murmur, best heard at apex with bell of stethoscope
Murmur Grading
- Grade I: Very faint, heard only in quiet environment
- Grade II: Quiet but readily heard
- Grade III: Moderately loud, no thrill
- Grade IV: Loud with palpable thrill
- Grade V: Very loud, thrill present, audible with stethoscope barely on chest
- Grade VI: Audible with stethoscope not touching chest
Abnormal Cardiac Findings
Pericardial Friction Rub
- Scratchy, grating sound heard throughout cardiac cycle
- Caused by inflammation of pericardial surfaces (pericarditis)
- Best heard at left lower sternal border with patient leaning forward
- May have up to three components (atrial systole, ventricular systole, ventricular diastole)
Patent Ductus Arteriosus
- Congenital heart defect where connection between pulmonary artery and aorta fails to close
- Produces continuous "machinery" murmur heard throughout systole and diastole
- Best heard in left infraclavicular area
Jugular Venous Pressure (JVP)
- Reflects right atrial pressure
- Elevated JVP suggests right heart failure, tricuspid regurgitation, or pericardial tamponade
- Assessed with patient at 45° angle, measuring height of pulsation above sternal angle
Peripheral Vascular Assessment
Arterial Pulses
- Locations:
- Carotid: Neck, medial to sternocleidomastoid
- Brachial: Antecubital fossa, medial to biceps tendon
- Radial: Lateral wrist
- Femoral: Below inguinal ligament, midway between pubic symphysis and anterior superior iliac spine
- Popliteal: Behind knee in popliteal fossa
- Dorsalis pedis: Dorsum of foot between 1st and 2nd metatarsals
- Posterior tibial: Behind medial malleolus
Pulse Grading
- 0: Absent
- 1+: Diminished
- 2+: Normal
- 3+: Increased
- 4+: Bounding
Arterial Insufficiency
- Subjective symptoms:
- Intermittent claudication (leg pain with walking that resolves with rest)
- Rest pain (severe ischemia)
- Cold extremities
- Numbness or paresthesias
- Physical findings:
- Diminished or absent pulses
- Pallor on elevation
- Dependent rubor
- Delayed capillary refill
- Hair loss
- Shiny, atrophic skin
- Ulceration (especially at pressure points)
- Gangrene in severe cases 1
Venous Insufficiency
- Subjective symptoms:
- Aching, heaviness in legs
- Swelling that worsens with prolonged standing
- Nocturnal leg cramps
- Pruritus
- Physical findings:
- Edema
- Varicose veins
- Hyperpigmentation
- Lipodermatosclerosis
- Venous ulcers (typically medial malleolus)
- Atrophie blanche (white scarring)
Carotid Bruit
- Blowing sound heard over carotid artery
- Suggests turbulent flow due to stenosis
- Associated with increased stroke risk
Differential Diagnosis of Chest Pain
Cardiac Causes
- Acute coronary syndrome (unstable angina, NSTEMI, STEMI)
- Stable angina
- Pericarditis
- Aortic dissection
- Valvular disease (especially aortic stenosis)
Pulmonary Causes
- Pulmonary embolism
- Pneumothorax
- Pleuritis
- Pneumonia
Gastrointestinal Causes
- GERD
- Esophageal spasm
- Peptic ulcer disease
- Biliary colic
- Pancreatitis
Musculoskeletal Causes
- Costochondritis
- Muscle strain
- Rib fracture
- Herpes zoster
Key Questions for Chest Pain Assessment
- Character: Pressure, sharp, burning, tearing?
- Location: Central, left-sided, radiating?
- Onset: Sudden or gradual?
- Duration: Seconds, minutes, hours?
- Exacerbating/relieving factors: Exertion, rest, position, nitroglycerin?
- Associated symptoms: Dyspnea, diaphoresis, nausea, syncope?
Special Considerations
Hemodynamic Changes During Pregnancy
- Increased blood volume (30-50%)
- Increased cardiac output (30-50%)
- Decreased systemic vascular resistance
- Physiologic murmurs common (flow murmurs)
Family History Importance
- Premature coronary artery disease
- Sudden cardiac death
- Cardiomyopathies
- Congenital heart disease
- Familial hyperlipidemia
- Arrhythmias
Common Pitfalls and Caveats
- Failing to distinguish between cardiac and non-cardiac chest pain
- Missing subtle signs of arterial insufficiency before tissue damage occurs
- Overlooking venous insufficiency as cause of leg symptoms
- Attributing all murmurs to pathology (some are benign flow murmurs)
- Inadequate assessment of peripheral pulses in patients with cardiovascular risk factors
- Failure to recognize that peripheral arterial disease is a marker for systemic atherosclerosis 1
A systematic approach to cardiac and peripheral vascular assessment provides crucial information for diagnosis, risk stratification, and management of cardiovascular conditions, significantly impacting patient morbidity and mortality.