What is the differential diagnosis for a patient with diabetes (diabetes mellitus) and mucormycosis infection in the kidney who has computed tomography (CT) chest findings of a calcified granuloma in the lower lung?

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Differential Diagnosis for Patient with Diabetes, Mucormycosis Infection in Kidney, and Calcified Granuloma in Lower Lung

  • Single Most Likely Diagnosis
    • Histoplasmosis: This is a fungal infection that can cause calcified granulomas in the lungs and is more likely in immunocompromised patients, such as those with diabetes. The presence of mucormycosis, another fungal infection, suggests an immunocompromised state, making histoplasmosis a plausible diagnosis.
  • Other Likely Diagnoses
    • Tuberculosis (TB): TB can cause calcified granulomas in the lungs and is a common infection in immunocompromised patients. The patient's diabetes and mucormycosis infection increase the likelihood of TB.
    • Coccidioidomycosis: This fungal infection is common in certain regions and can cause calcified granulomas in the lungs. Immunocompromised patients, such as those with diabetes, are more susceptible to severe forms of the disease.
  • Do Not Miss Diagnoses
    • Cryptococcosis: Although less common, cryptococcosis is a potentially deadly fungal infection that can cause lung lesions and is more likely in immunocompromised patients. Missing this diagnosis could be fatal.
    • Nocardiosis: This bacterial infection can cause lung lesions and is more common in immunocompromised patients. It can be deadly if not treated promptly.
  • Rare Diagnoses
    • Blastomycosis: This fungal infection can cause calcified granulomas in the lungs but is less common than other fungal infections. It is still a possibility in immunocompromised patients.
    • Paracoccidioidomycosis: This fungal infection is rare in most regions but can cause lung lesions and is more common in immunocompromised patients. It is an important consideration in patients with a travel history to endemic areas.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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