How do you interpret an electrocardiogram (EKG)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: October 3, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

How to Read an EKG: A Systematic Approach

A systematic approach to EKG interpretation is essential for accurate diagnosis of cardiac conditions, with proper analysis following a structured methodology to avoid missing critical information.

Basic Principles of EKG Interpretation

The electrocardiogram (EKG) is a fundamental diagnostic tool that provides critical information about cardiac electrical activity. A systematic approach ensures comprehensive evaluation and accurate diagnosis.

Step 1: Rate and Rhythm Assessment

  • Calculate the heart rate by counting the number of QRS complexes in a 6-second strip and multiplying by 10, or by using the formula 300 divided by the number of large boxes between consecutive R waves 1
  • Identify the underlying rhythm - sinus rhythm is characterized by a P wave before each QRS complex with consistent PR interval 1
  • Normal sinus rhythm has a rate between 60-100 beats per minute in adults, while sinus bradycardia (<60 bpm) and sinus tachycardia (>100 bpm) may be normal variants in athletes or during physiological stress 1
  • Note any irregularities in rhythm, such as premature beats, pauses, or completely irregular patterns that might suggest atrial fibrillation 1

Step 2: Intervals and Conduction Analysis

  • Measure the PR interval (normal: 120-200 ms) to assess AV conduction 1
  • Evaluate QRS duration (normal: <120 ms) to identify ventricular conduction delays 1
  • Calculate the QT interval corrected for heart rate (QTc) using Bazett's formula, with normal values being <450 ms for men and <460 ms for women 1
  • Identify any conduction abnormalities such as AV blocks, bundle branch blocks, or pre-excitation 1

Step 3: Axis Determination

  • Determine the electrical axis by examining leads I and aVF:
    • Normal axis: +90° to -30° (positive in both leads I and aVF)
    • Left axis deviation: -30° to -90° (positive in lead I, negative in aVF)
    • Right axis deviation: +90° to +180° (negative in lead I, positive in aVF)
    • Extreme axis deviation: +180° to -90° (negative in both leads I and aVF) 1

Step 4: Chamber Enlargement Assessment

  • Look for voltage criteria for ventricular hypertrophy:
    • Left ventricular hypertrophy: S in V1 + R in V5 or V6 >3.5 mV
    • Right ventricular hypertrophy: R in V1 + S in V5 or V6 >1.1 mV 1
  • Assess for atrial enlargement patterns 1

Step 5: Ischemia, Injury, and Infarction Evaluation

  • Examine for ST-segment deviations:
    • ST elevation (>0.1 mV in limb leads or >0.15-0.2 mV in precordial leads) may indicate acute injury 1
    • ST depression (≥0.05 mV) may suggest ischemia 1
  • Look for T-wave abnormalities (inversion, hyperacute, flattening) 1
  • Identify pathological Q waves (>0.04 seconds or >25% of the R wave amplitude) suggesting myocardial infarction 1
  • Note the location of abnormalities to determine the affected coronary territory 1

Special Considerations

Normal Variants vs. Pathological Findings

  • Some findings may be normal variants, especially in athletes:
    • Sinus bradycardia (≥30 beats/min)
    • Sinus arrhythmia (respiratory variation in heart rate)
    • First-degree AV block (PR interval 200-400 ms)
    • Incomplete right bundle branch block
    • Early repolarization
    • Isolated QRS voltage criteria for ventricular hypertrophy 1

Age and Population-Specific Considerations

  • In children older than 1 month, T waves are often inverted in leads V1, V2, and V3 1
  • In adolescents (12-20 years), T waves may be slightly inverted in aVF and V1 1
  • In Black athletes, J-point elevation with convex ST-segment elevation followed by T-wave inversion in leads V2-V4 may be a normal variant 1
  • Juvenile T-wave pattern (T-wave inversion in V2-V3) is normal in athletes under 16 years 1

Common Pitfalls to Avoid

  • Misplacement of electrodes, particularly precordial leads, can significantly alter EKG interpretation and lead to false diagnoses 1
  • Inadequate filtering settings can distort waveforms and affect measurements 1
  • Over-reliance on computer interpretation without physician verification can lead to diagnostic errors, as computer accuracy varies widely (0-94%) depending on the abnormality 1
  • Failure to compare with previous EKGs when available can miss important changes 1
  • Interpreting EKG findings in isolation without considering clinical context may lead to inappropriate management decisions 1

Practical Approach for Beginners

  • The RIRI approach (Rate, Intervals, Rhythm, Ischemia/Infarction) offers a reliable and systematic method for EKG interpretation 2
  • Regular practice with varied EKGs is essential for developing proficiency 1
  • Formal training significantly improves interpretation accuracy compared to self-learning from books 3
  • When in doubt, particularly for 12-lead EKG interpretation, consultation with more experienced clinicians is recommended 3

Remember that while computer analysis can be helpful, it should never replace interpretation by a qualified physician, as errors in computer interpretation remain common 1. Proper EKG interpretation requires a combination of knowledge, skill, and clinical experience to effectively correlate findings with the patient's clinical presentation.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

A novel systematic approach to ECG interpretation.

Dynamics (Pembroke, Ont.), 2005

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.