Differential Diagnosis for Toddler Sweating at Night

• Single most likely diagnosis
  • Overheating or overbundling: This is the most common reason for a toddler to sweat at night, as their ability to regulate body temperature is still developing, and they may be dressed too warmly for the room temperature.
• Other Likely diagnoses
  • Sleep environment: A room that is too hot or humid can cause a toddler to sweat.
  • Normal variation: Some toddlers may naturally sweat more than others, especially during deep sleep phases.
  • Infection: Mild infections such as a cold or ear infection can cause an increase in body temperature, leading to sweating.
• Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
  • Meningitis or sepsis: Although rare, these serious infections can present with fever and sweating, and it's crucial to consider them to avoid delayed diagnosis.
  • Hypothyroidism: Although uncommon, hypothyroidism can cause excessive sweating, among other symptoms.
  • Sleep apnea: While less common in toddlers, sleep apnea can lead to increased sweating due to the physical stress of breathing difficulties during sleep.
• Rare diagnoses
  • Pheochromocytoma: A rare tumor that can cause excessive sweating due to the excessive production of adrenaline.
  • Hyperthyroidism: An overactive thyroid gland can lead to increased sweating, among other symptoms, though this is rare in toddlers.
  • Neurological disorders: Certain rare neurological conditions can affect the body's ability to regulate temperature, leading to excessive sweating.