Definition of a Difficult Airway
A difficult airway is defined as a clinical situation in which a physician trained in anesthesia care experiences anticipated or unanticipated difficulty or failure with face-mask ventilation, laryngoscopy, ventilation using a supraglottic airway, tracheal intubation, extubation, or invasive airway. 1
Specific Types of Difficult Airways
Difficult Facemask Ventilation
- Occurs when it is not possible to provide adequate ventilation (confirmed by end-tidal carbon dioxide detection) due to:
- Inadequate mask seal
- Excessive gas leak
- Excessive resistance to the ingress or egress of gas 1
Difficult Laryngoscopy
- Defined as inability to visualize any portion of the vocal cords after multiple attempts at laryngoscopy 1
- May be further subdivided into grades according to the Cormack & Lehane classification, with grade 3 being subdivided into 3a (epiglottis can be lifted) and 3b (epiglottis cannot be lifted from the posterior pharyngeal wall) 1
Difficult Supraglottic Airway Ventilation
- Occurs when adequate ventilation cannot be provided due to:
- Difficult supraglottic airway placement
- Multiple attempts required for placement
- Inadequate supraglottic airway seal
- Excessive gas leak
- Excessive resistance to gas flow 1
Difficult or Failed Tracheal Intubation
- Defined as either:
- Tracheal intubation requiring multiple attempts
- Complete failure of tracheal intubation after multiple attempts 1
Difficult or Failed Tracheal Extubation
- The loss of airway patency and adequate ventilation after removal of a tracheal tube or supraglottic airway from a patient with a known or suspected difficult airway (an "at risk" extubation) 1
Difficult or Failed Invasive Airway
- Anatomic features or abnormalities that reduce or prevent the likelihood of successfully placing an airway into the trachea through the front of the neck 1
Signs of Inadequate Ventilation
- Absent or inadequate exhaled carbon dioxide
- Absent or inadequate chest movement
- Absent or inadequate breath sounds
- Auscultatory signs of severe obstruction
- Cyanosis
- Gastric air entry or dilatation
- Decreasing or inadequate oxygen saturation
- Absent or inadequate exhaled gas flow as measured by spirometry
- Anatomic lung abnormalities detected by lung ultrasound
- Hemodynamic changes associated with hypoxemia or hypercarbia (hypertension, tachycardia, bradycardia, arrhythmia)
- Changed mental status or somnolence 1
Clinical Application
- These definitions apply to all airway management and anesthetic care delivered in:
- Inpatient settings (perioperative, non-operating room, emergency department, critical care)
- Ambulatory settings (surgery centers, office-based procedures) 1
- The guidelines are intended for use by anesthesiologists and all others who perform anesthesia care or airway management 1
Important Considerations
- Difficult airways should be anticipated whenever possible through comprehensive assessment 2
- The incidence of difficult mask ventilation varies widely (0.08% to 15%) depending on the criteria used 3
- Predictors of difficult mask ventilation include obesity, age >55 years, history of snoring, lack of teeth, presence of beard, Mallampati Class III or IV, and abnormal mandibular protrusion 3
- Difficult tracheal intubation is more frequent in patients who experience difficult mask ventilation 3
- The most critical airway situation, "cannot intubate, cannot oxygenate," occurs rarely (0.0019-0.04%) but can have severe consequences including hypoxic brain damage and death 4
Management Approach
- Management should follow a structured algorithm with Plans A through D as outlined by airway management societies 1
- Each plan should be implemented sequentially based on the outcome of the previous plan 1
- Preparedness for failed intubation and use of adjuncts such as video laryngoscopy, supraglottic airway devices, and awake intubation techniques are essential components of difficult airway management 2