Recommended Approach for Weight Loss
The most effective approach for weight loss combines a moderately reduced-calorie diet, increased physical activity, and behavioral strategies to facilitate adherence to diet and activity recommendations. 1
Dietary Strategies
Caloric Reduction
- Create an energy deficit of 500-1000 kcal/day through reduced caloric intake, typically prescribing 1200-1500 kcal/day for women and 1500-1800 kcal/day for men 1
- This caloric deficit should result in weight loss of approximately 1-2 pounds per week 1
- Weight loss is typically maximal at 6 months, with smaller losses maintained for up to 2 years 1
Macronutrient Composition
- Reducing dietary fat to less than 30% of total energy intake can facilitate weight loss by reducing total energy intake 1
- Low-carbohydrate diets (restricting total carbohydrate to <130 g/day) are not recommended for long-term treatment of overweight/obesity due to unknown long-term effects 1
- No single macronutrient composition has shown clear long-term superiority - the most important factor is creating and maintaining a caloric deficit 1, 2
Physical Activity
- Incorporate regular aerobic physical activity (such as brisk walking) for at least 150 minutes/week (30 minutes/day most days of the week) 1
- Higher levels of physical activity (200-300 minutes/week) are recommended for long-term weight maintenance 1, 3
- While exercise alone has modest effects on initial weight loss, it significantly improves insulin sensitivity and is crucial for long-term weight maintenance 1
- High-intensity physical activity is more effective than moderate activity for reducing body fat while preserving muscle mass 4
Behavioral Strategies
- Include structured behavior change programs with regular self-monitoring of food intake, physical activity, and weight 1
- Behavioral approaches include self-monitoring, stress management, stimulus control, problem-solving, contingency management, cognitive restructuring, and social support 1
- Weekly weighing is particularly important for long-term weight maintenance 1
- Structured programs should provide frequent contact (initially weekly) with trained interventionists 1
Comprehensive Approach
- The most effective weight loss interventions combine all three components: diet, physical activity, and behavioral strategies 1
- Structured intensive lifestyle programs produce average weight losses of 5-7% of starting weight over 6 months 1
- Long-term success requires continued intervention contacts (at least bimonthly) after the first year to minimize weight regain 1
Supplementary Approaches
- Meal replacements (liquid or solid prepackaged) can be effective when used to replace one or two meals daily, but must be continued for weight maintenance 1
- For BMI ≥30 kg/m² or ≥27 kg/m² with comorbidities, FDA-approved weight loss medications may be considered as part of a comprehensive program 1, 5
- Multivitamin supplementation is recommended when using significant caloric restriction to prevent nutrient deficiencies 5, 6
Common Pitfalls and Caveats
- Standard weight reduction diets alone, without behavioral support and physical activity, typically result in poor long-term outcomes and weight regain 1
- Very low calorie diets (<800 kcal/day) can produce rapid weight loss but commonly result in weight regain when normal eating is resumed 1
- After dieting, hormonal mechanisms that stimulate appetite remain elevated for at least a year, making weight maintenance challenging 7
- Caloric reduction without attention to nutrient density may lead to inadequate intake of essential nutrients 6
- Weight loss plateaus are common and should be anticipated as part of the normal process 2