Treatment of Perforated Eardrum
For a perforated eardrum, mechanical removal of debris is the preferred treatment method, avoiding irrigation which could cause complications in cases of tympanic membrane perforation. 1
Initial Assessment and Management
- Carefully assess the perforation by history and physical examination to determine the cause (trauma, infection), size, and location of the perforation 1
- Keep the ear dry to prevent infection, as moisture can enter the middle ear through the perforation 2
- Avoid irrigation of the ear canal in patients with perforated eardrums as this can cause vertigo and introduce toxins to the middle ear 1
- Use manual removal with appropriate instrumentation (curette, forceps, suction) under direct visualization to clear debris when necessary 1
Treatment Based on Cause
Traumatic Perforations
- Most traumatic perforations heal spontaneously within 1-3 months and require minimal intervention 2, 3
- Keep the ear dry and avoid water exposure by using ear plugs or cotton with petroleum jelly when showering 1
- Avoid inserting anything into the ear canal, including cotton-tipped swabs 1
Infection-Related Perforations
Acute Otitis Media with Perforation:
- Treat with appropriate oral antibiotics 2
- For chronic suppurative otitis media with perforated tympanic membrane in patients 12 years and older:
- Topical antibiotic therapy: Ten drops (0.5 mL, 1.5 mg ofloxacin) instilled into the affected ear twice daily for fourteen days 4
- Warm the solution by holding the bottle in hand for 1-2 minutes to avoid dizziness 4
- Patient should lie with affected ear upward during instillation 4
- Pump the tragus 4 times to facilitate penetration into the middle ear 4
- Maintain position for five minutes after instillation 4
For Aspergillus Otomycosis with Perforation:
- Topical therapy with irrigating solutions of boric acid, acetic acid, or azole cream may be effective 1
- For refractory cases with perforated tympanic membranes, voriconazole, posaconazole, or itraconazole may be appropriate 1
Monitoring and Follow-up
- Most small perforations heal spontaneously within 1-3 months 3, 5
- Healing rates are generally good (82-95%) regardless of perforation size, though larger perforations take longer to heal 3
- Factors affecting healing:
When to Refer to an Otolaryngologist
- Perforations that persist beyond one month 5
- Presence of alarming symptoms such as:
- Chronic perforations that may require surgical repair 2, 6
- Suspicion of cholesteatoma or other unsafe conditions 6
Surgical Options
- Tympanoplasty may be considered for perforations that do not heal spontaneously 1, 6
- Cartilage tympanoplasty provides better structural outcomes (fewer postoperative TM perforations) compared to temporalis muscle fascia, though hearing outcomes are similar 1
- Novel adjuvant therapies such as biomolecules (fibroblast growth factor) with scaffolding materials have shown promising results for chronic perforations 1