What vaccines does a 12-year-old need?

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Last updated: October 3, 2025View editorial policy

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Recommended Vaccines for a 12-Year-Old

A 12-year-old should receive the Tdap vaccine, meningococcal conjugate vaccine (MenACWY), and HPV vaccine series as part of their routine immunization schedule. 1

Core Vaccines Recommended at Age 12

Tetanus, Diphtheria, and Acellular Pertussis (Tdap)

  • Administer at age 11-12 years as a single dose to those who have completed their childhood DTP/DTaP vaccination series 1
  • This serves as a booster to maintain protection against tetanus and diphtheria while providing protection against pertussis 1
  • The preferred age for Tdap vaccination is 11-12 years to reduce morbidity associated with pertussis in adolescents 1

Meningococcal Conjugate Vaccine (MenACWY)

  • Administer at age 11-12 years as a single dose 1
  • Provides protection against meningococcal disease caused by serogroups A, C, W, and Y 2
  • A booster dose will be needed at age 16 years 2

Human Papillomavirus (HPV) Vaccine

  • Administer the first dose at age 11-12 years 1
  • Follow with a second dose 2 months after the first dose and a third dose 6 months after the first dose 1
  • HPV vaccination helps prevent HPV-associated cancers 2
  • As of 2019, vaccination coverage with ≥1 dose of HPV vaccine was 71.5%, and 54.2% of adolescents were up to date with the HPV vaccination series 2

Additional Vaccines to Consider

Influenza Vaccine

  • Administer annually to all adolescents 1
  • Only trivalent inactivated influenza vaccine (TIV) should be used for immunocompromised persons 1
  • For healthy adolescents, either live attenuated influenza vaccine (LAIV) or TIV may be used 1

Catch-Up Vaccines (if not previously received)

  • Varicella (Chickenpox) Vaccine:

    • Should be administered if the adolescent has not been vaccinated and does not have a reliable history of chickenpox 1
    • For susceptible persons ≥13 years of age, two doses separated by 4-8 weeks are recommended 1
  • Hepatitis A Vaccine:

    • If not previously vaccinated, administer 2 doses at least 6 months apart 1
  • Hepatitis B Vaccine:

    • Complete the 3-dose series if not previously vaccinated 3
  • MMR (Measles, Mumps, Rubella):

    • Ensure the adolescent has received 2 doses 1, 3

Important Considerations

Simultaneous Administration

  • All indicated vaccines can and should be administered during the same visit to increase the likelihood that adolescents receive each vaccine on schedule 1
  • Each vaccine should be administered using a separate syringe at a different anatomic site 1
  • Some experts recommend administering no more than two injections per muscle, separated by at least one inch 1

Special Populations

  • Adolescents with chronic health conditions (asthma, diabetes, etc.) should receive annual influenza vaccination 1
  • Immunocompromised adolescents may need adjusted vaccination schedules and should only receive inactivated vaccines when alternatives exist 1

Vaccination Coverage

  • Despite recommendations, vaccination coverage varies widely among states 3
  • As of 2019, coverage rates were 88.9% for ≥1 dose of MenACWY and 71.5% for ≥1 dose of HPV vaccine 2
  • Providers should use every health-care visit as an opportunity to review adolescents' immunization histories 4

Potential Barriers

  • The COVID-19 pandemic disrupted routine vaccination services, with decreased vaccine orders observed for Tdap, HPV, and MenACWY vaccines in 2020 2
  • Ensuring that routine immunization services for adolescents are maintained is essential for continuing protection against vaccine-preventable diseases 2

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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