What is the maximum recommended daily dose of Mucomix (acetylcysteine) tablets?

Maximum Daily Dose of Mucomix (Acetylcysteine) Tablets

The maximum recommended daily dose of Mucomix (acetylcysteine) tablets is 1600 mg per day.

Dosage Information

• Acetylcysteine is commonly used as a mucolytic agent with both mucokinetic and expectorant properties 1
• Standard oral dosing typically ranges from 200-600 mg per day, divided into multiple doses 1
• For respiratory conditions requiring mucolytic therapy, doses are typically administered 2-3 times daily 1
• The maximum total daily dose should not exceed 1600 mg to avoid potential neurological toxicity 2

Clinical Applications

• Acetylcysteine functions as more than just a mucolytic agent - it also acts as:

  • A free-radical scavenger 1
  • A precursor of glutathione 1
  • A bronchorrheic agent when used in aerosol form 1
  • An expectorant and mucoregulator when administered orally 1

• Acetylcysteine is well-established as the treatment of choice for acetaminophen poisoning, where higher doses may be used under medical supervision 1

Special Considerations

• Dosage may need adjustment in patients with:

  • Severe hepatic impairment 2
  • Renal dysfunction 2
  • Concurrent medications that may interact with acetylcysteine 2

• When used for respiratory conditions, the effectiveness should be monitored through:

  • Improvement in respiratory symptoms 1
  • Changes in sputum characteristics 1
  • Overall respiratory function 1

Common Side Effects

• Gastrointestinal disturbances (nausea, vomiting) 2
• Unpleasant odor or taste 1
• Rarely, bronchospasm (particularly in patients with hyperreactive airways) 1

Remember that while acetylcysteine has multiple therapeutic applications beyond its mucolytic properties, the maximum daily oral dose of 1600 mg should be respected to avoid potential adverse effects.