Treatment of Dental Bleeding
For dental bleeding, the most effective first-line treatment is applying direct pressure with gauze, potentially soaked with tranexamic acid, which can improve hemostasis by a factor of 1.6 compared to dry gauze alone. 1, 2
Initial Management
- Clean the bleeding wound with saline solution or tap water 1
- Apply direct pressure to the bleeding site using gauze or cotton 1, 3
- For improved efficacy, use gauze soaked with tranexamic acid (TXA) 2, 4
- Maintain compression for at least 30 minutes for most minor bleeding episodes 2, 3
Pharmacological Management
- Tranexamic acid (TXA) is highly effective as a topical agent for dental bleeding:
Advanced Hemostatic Measures
If bleeding persists despite initial compression measures, consider escalating treatment:
- Apply local hemostatic agents (e.g., gelatin sponge, collagen fleece) 2, 4
- Place sutures at the bleeding site 3, 4
- For severe cases, consider fibrin sealants or human thrombin products (e.g., Floseal®) 4
- Electrocautery may be necessary in resistant cases 3
Special Considerations for Patients on Anticoagulants
For patients on vitamin K antagonists (VKAs):
- Continue VKA therapy with coadministration of tranexamic acid mouthwash rather than interrupting anticoagulation 1
- If necessary, partial interruption (2-3 days before procedure) is preferable to complete interruption 1
- Risk of bleeding with continued VKA therapy is low (<5%) and typically self-limiting 1
For patients on dual antiplatelet therapy:
Risk Factors for Difficult-to-Control Bleeding
- Patients taking antithrombotic agents have approximately twice the risk of requiring complex hemostatic measures 3
- Presence of inflammation at the bleeding site increases risk of prolonged bleeding by a factor of 10 6
- Multiple root extractions (especially 3-root extractions) increase bleeding risk by a factor of 7.3 6
- Minor oral surgery procedures (beyond simple extractions) may require more aggressive hemostatic approaches 3
When to Seek Advanced Care
Refer for specialized management when:
- Bleeding persists despite appropriate local measures for more than 30-60 minutes 3, 6
- Patient has known bleeding disorders requiring factor replacement or other specialized interventions 7
- Significant hemodynamic instability or major bleeding with hemoglobin decrease ≥2 g/dL 1
- Bleeding occurs at a critical site or is life-threatening 1