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Differential Diagnosis for Inner Eyelid Red and Swollen

  • Single most likely diagnosis
    • Conjunctivitis: This is the most common cause of inner eyelid redness and swelling, often due to viral or bacterial infections, or allergic reactions. The symptoms can include redness, itching, discharge, and swelling of the conjunctiva, which is the membrane covering the white part of the eyes and the inner eyelids.
  • Other Likely diagnoses
    • Blepharitis: Inflammation of the eyelids, which can cause redness, swelling, and itching. It's often associated with a bacterial or demodex mite infestation.
    • Dry Eye Syndrome: Although primarily causing discomfort and vision problems, severe cases can lead to inflammation and redness of the inner eyelid.
    • Allergic Rhinitis: Seasonal or perennial allergies can cause conjunctival symptoms including redness and swelling of the inner eyelids.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Orbital Cellulitis: A serious infection of the tissues surrounding the eye, which can cause redness, swelling, and pain. It requires prompt medical attention to prevent serious complications.
    • Sjögren's Syndrome: An autoimmune disorder that can cause dry eyes and mouth, and in severe cases, can lead to significant ocular and systemic complications.
    • Angioedema: A condition characterized by rapid swelling of the skin and mucous membranes, which can be life-threatening if it involves the airways.
  • Rare diagnoses
    • Stevens-Johnson Syndrome: A rare but serious disorder of the skin and mucous membranes, often triggered by medications or infections, which can cause severe eye symptoms including inner eyelid redness and swelling.
    • Ocular Rosacea: A condition that causes inflammation of the eyes and can lead to symptoms such as redness, swelling, and dryness, often associated with rosacea of the skin.
    • Graft-Versus-Host Disease (GVHD): In patients who have undergone bone marrow or stem cell transplants, GVHD can cause a variety of symptoms including eye problems like conjunctivitis and dry eye syndrome.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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