What is the cause of postprandial (after eating) abdominal pain?

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Differential Diagnosis for Abdominal Pain with Eating

  • Single Most Likely Diagnosis
    • Peptic Ulcer Disease: This is a common cause of abdominal pain related to eating, as the pain often worsens with food intake due to increased acid production.
  • Other Likely Diagnoses
    • Gastroesophageal Reflux Disease (GERD): Symptoms can include abdominal pain that worsens with eating, especially after consuming trigger foods.
    • Functional Dyspepsia: Characterized by recurring abdominal pain or discomfort that is associated with eating, without an identifiable cause.
    • Irritable Bowel Syndrome (IBS): While primarily associated with alterations in bowel habits, some patients with IBS may experience abdominal pain that is triggered or worsened by eating.
  • Do Not Miss Diagnoses
    • Acute Mesenteric Ischemia: A life-threatening condition that can present with severe abdominal pain out of proportion to physical examination findings, which may be exacerbated by eating due to increased demand for intestinal blood flow.
    • Pancreatitis: Can cause severe abdominal pain that may be worsened by eating, especially fatty foods, due to stimulation of the pancreas.
    • Gastric Cancer: Although less common, it is crucial not to miss this diagnosis, as early detection significantly improves prognosis. Abdominal pain related to eating can be a symptom.
  • Rare Diagnoses
    • Eosinophilic Gastroenteritis: A rare condition characterized by eosinophilic infiltration of the gastrointestinal wall, which can cause abdominal pain related to eating due to food allergies or sensitivities.
    • Celiac Disease: An autoimmune reaction to gluten, leading to small intestine damage and potentially causing abdominal pain after eating gluten-containing foods.
    • Intestinal Obstruction: While not typically associated directly with eating, an obstruction can cause abdominal pain that may seem to worsen with attempts to eat due to increased intestinal contractions against the obstruction.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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