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Differential Diagnosis for Pain to Bottom of and Lateral Foot

Single Most Likely Diagnosis

  • Plantar Fasciitis: This condition is the most common cause of heel pain and can also affect the bottom and lateral aspects of the foot. It is characterized by inflammation of the plantar fascia, a band of tissue that supports the arch of the foot.

Other Likely Diagnoses

  • Peroneal Tendinopathy: Inflammation or degeneration of the peroneal tendons, which run along the lateral aspect of the foot and ankle, can cause pain in this area.
  • Lateral Plantar Nerve Entrapment: Compression of the lateral plantar nerve can cause pain, numbness, and tingling in the lateral and bottom aspects of the foot.
  • Cuboid Syndrome: This condition involves the cuboid bone in the midfoot and can cause pain on the lateral side of the foot, especially when weight-bearing.

Do Not Miss Diagnoses

  • Deep Vein Thrombosis (DVT): Although less common, DVT can cause foot pain, especially if the clot is located in the deep veins of the foot or ankle. It's crucial to consider this diagnosis due to its potential for severe complications, such as pulmonary embolism.
  • Osteomyelitis or Septic Arthritis: Infections of the bone or joint can cause severe pain and have significant consequences if not promptly treated.
  • Tarsal Tunnel Syndrome: Compression of the posterior tibial nerve can cause pain, numbness, and tingling in the foot, similar to carpal tunnel syndrome in the hand.

Rare Diagnoses

  • Tarsal Coalition: An abnormal connection between two or more of the tarsal bones in the foot can cause pain, especially during activities that involve twisting or turning.
  • Freiberg's Disease: A rare condition that affects the metatarsal bones, causing pain and stiffness in the foot, particularly in adolescents.
  • Erythromelalgia: A disorder that causes burning pain, heat, and redness in the feet, often related to underlying conditions such as myeloproliferative disorders.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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