What is the treatment for a superficial cat scratch?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: October 4, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Treatment for Superficial Cat Scratch

The recommended treatment for a superficial cat scratch is to promptly wash the wound with soap and water, followed by application of a topical antibiotic and covering with a clean occlusive dressing to promote healing. 1

Initial Wound Care

  • Immediately clean the wound thoroughly with soap and water to reduce the risk of infection 1
  • Irrigation with tap water is effective for cleaning the wound and has been shown to be as good as or better than other irrigation solutions in reducing infection rates 1
  • Higher volumes of irrigation fluid (100-1000 mL) are more effective than lower volumes 1

Wound Management After Cleaning

  • Apply a topical antibiotic to keep the wound moist and prevent drying 1
  • Cover the wound with a clean occlusive dressing to promote faster healing 1
  • Evidence shows significantly shorter healing time for abrasions treated with occlusive dressings or topical antibiotics versus no dressing or antibiotic 1

Special Considerations for Cat Scratches

  • Cat scratches carry a specific risk for Bartonella infection (cat scratch disease) 1
  • Prompt washing of cat scratch sites is specifically recommended to reduce the risk of Bartonella infection 1
  • Avoid allowing cats to lick open wounds or cuts to prevent potential infections 1

When to Seek Medical Attention

  • Signs of infection requiring medical attention include:

    • Increasing redness, swelling, warmth, or pain around the wound 1
    • Development of red streaks extending from the wound 1
    • Fever or systemic symptoms 1
    • Lymph node enlargement (particularly concerning for cat scratch disease) 1, 2
  • Immunocompromised individuals (especially HIV-infected persons) should be particularly vigilant about cat scratches due to increased risk of severe Bartonella infections 1

Treatment for Infected Cat Scratches

  • If cat scratch disease develops (characterized by lymphadenopathy), azithromycin is the recommended treatment 1:

    • For patients >45 kg: 500 mg on day 1 followed by 250 mg for 4 additional days
    • For patients <45 kg: 10 mg/kg on day 1 and 5 mg/kg for 4 more days
  • For severe or systemic infections, other effective antibiotics include rifampin, ciprofloxacin, gentamicin, or trimethoprim-sulfamethoxazole 2, 3

Prevention of Future Cat Scratches

  • Avoid activities that might result in cat scratches 1
  • Implement flea control for cats to reduce the risk of Bartonella infection 1
  • For immunocompromised individuals, consider adopting cats older than 1 year of age in good health 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Treatment of cat-scratch disease.

Current opinion in pediatrics, 2001

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.