What is the recommended dose of ibuprofen (Nonsteroidal Anti-Inflammatory Drug (NSAID)) for a 76 pound (weight) girl?

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Ibuprofen Dosing for a 76 lb Girl

For a 76 pound (34.5 kg) girl, the recommended dose of ibuprofen is 200-345 mg every 6-8 hours, not to exceed 1380 mg per day. 1, 2

Dosage Calculation

  • The standard pediatric dosing for ibuprofen is 5-10 mg/kg per dose 2
  • For a 76 lb (34.5 kg) child:
    • Minimum dose: 5 mg/kg × 34.5 kg = 172.5 mg (round to 200 mg)
    • Maximum dose: 10 mg/kg × 34.5 kg = 345 mg 1, 2
  • Frequency: Can be administered 3-4 times per day (every 6-8 hours) 2
  • Maximum daily dose: 30-40 mg/kg/day = 1035-1380 mg/day 2

Administration Guidelines

  • Ibuprofen should be taken with food to minimize gastrointestinal side effects 3
  • Liquid formulations are available for easier administration if needed 3
  • The duration of analgesic effect is approximately 6 hours for doses of 200 mg and higher 4
  • For fever reduction, maximum effect occurs 3-4 hours after administration 1

Safety Considerations

  • Ibuprofen has been shown to be well-tolerated in children, with fewer adverse effects than in adults 1, 3
  • Ensure proper hydration when administering ibuprofen to prevent potential renal effects 2
  • Short-term use (less than 10 days) at recommended doses has an excellent safety profile 5
  • Avoid use if the child has:
    • Known hypersensitivity to NSAIDs 3
    • History of gastrointestinal bleeding 3
    • Significant renal impairment 2, 3

Common Formulations

  • Children's ibuprofen liquid: 100 mg/5 mL
  • Junior strength tablets/chewables: 100 mg
  • Adult tablets: 200 mg

Practical Dosing

For a 76 lb girl, the following doses would be appropriate:

  • Children's liquid (100 mg/5 mL): 10-17.5 mL per dose
  • Junior strength tablets: 2-3 tablets (200-300 mg) per dose
  • Adult tablets: 1-1.5 tablets (200-300 mg) per dose 1, 2

Comparison to Other Analgesics

  • Ibuprofen has been shown to be equally or more effective than acetaminophen (paracetamol) for pain relief and fever reduction in children 1, 4
  • It has a longer duration of action (6 hours) compared to acetaminophen (4-6 hours) 4
  • Ibuprofen has both analgesic and anti-inflammatory properties, making it particularly effective for pain associated with inflammation 3

References

Research

A general overview of the use of ibuprofen in paediatrics.

International journal of clinical practice. Supplement, 2003

Research

Ibuprofen: pharmacology, efficacy and safety.

Inflammopharmacology, 2009

Research

Review of the analgesic efficacy of ibuprofen.

International journal of clinical practice. Supplement, 2003

Research

Ibuprofen: a journey from prescription to over-the-counter use.

Journal of the Royal Society of Medicine, 2007

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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