What are the key steps in interpreting an electrocardiogram (EKG)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: October 5, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Key Steps in Interpreting an Electrocardiogram (EKG)

A systematic approach to EKG interpretation is essential for accurate diagnosis and appropriate clinical decision-making, focusing on rate, rhythm, intervals, axis, and morphology analysis.

Initial Assessment

  • Begin by calculating the heart rate by counting the number of QRS complexes in a 6-second strip and multiplying by 10, or using the formula 300 divided by the number of large boxes between consecutive R waves 1
  • Identify the underlying rhythm, looking for P waves before each QRS complex with consistent PR intervals to confirm sinus rhythm 1
  • Note any irregularities in rhythm, such as premature beats, pauses, or completely irregular patterns that might suggest atrial fibrillation 1
  • Evaluate the quality of the EKG recording and identify any technical artifacts that may affect interpretation 2

Interval and Conduction Analysis

  • Measure the PR interval (normal: 120-200 ms) to assess AV conduction 1
  • Evaluate QRS duration (normal: <120 ms) to identify ventricular conduction delays or bundle branch blocks 1
  • Calculate the QT interval corrected for heart rate (QTc) using Bazett's formula, with normal values being <450 ms for men and <460 ms for women 1
  • Identify any conduction abnormalities such as AV blocks, bundle branch blocks, or pre-excitation patterns 1

Axis Determination

  • Determine the electrical axis by examining leads I and aVF, with normal axis between +90° to -30° (positive in both leads I and aVF) 1
  • Identify left axis deviation: -30° to -90° (positive in lead I, negative in aVF) 1
  • Identify right axis deviation: +90° to +180° (negative in lead I, positive in aVF) 1
  • Note extreme axis deviation: +180° to -90° (negative in both leads I and aVF) 1

Chamber Enlargement Assessment

  • Look for voltage criteria for left ventricular hypertrophy: S in V1 + R in V5 or V6 >3.5 mV 1
  • Assess for atrial enlargement patterns in the P wave morphology 1
  • Consider these findings in the context of the patient's clinical presentation, as they may indicate underlying structural heart disease 3

Ischemia, Injury, and Infarction Evaluation

  • Examine for ST-segment deviations, with ST elevation (>0.1 mV in limb leads or >0.15-0.2 mV in precordial leads) potentially indicating acute injury 1
  • Look for T-wave abnormalities (inversion, hyperacute, flattening) that may suggest ischemia 1, 4
  • Identify pathological Q waves (>0.04 seconds or >25% of the R wave amplitude) suggesting myocardial infarction 1
  • Note the location of abnormalities to determine the affected coronary territory 5
  • Recognize that up-sloping ST-segment depression with positive T waves may indicate regional subendocardial ischemia associated with severe left anterior descending coronary artery obstruction 5

Clinical Context Integration

  • Always interpret the EKG in the context of the patient's clinical presentation, as the same EKG finding may have different implications depending on symptoms 2
  • Compare with previous EKGs when available to identify significant changes 1
  • Recognize that noncardiologists are more influenced by patient history in interpreting EKGs than cardiologists, making clinical context particularly important 2
  • Consider computer interpretations as helpful adjuncts but not substitutes for physician interpretation in clinical decision making 2

Common Pitfalls to Avoid

  • Avoid misplacement of electrodes, particularly precordial leads, which can significantly alter EKG interpretation 1
  • Avoid over-reliance on computer interpretation without physician verification, as errors in computer interpretation are still common 2
  • Be aware that many patients may have ST elevation due to non-ischemic causes, requiring careful clinical correlation 4
  • Recognize that interpretation of EKGs varies greatly, even among expert electrocardiographers 2
  • Avoid interpreting EKG findings in isolation without considering clinical context, which may lead to inappropriate management decisions 1

Maintaining Competency

  • Continuing medical education through seminars or self-assessment programs is encouraged to keep EKG interpretation skills current, especially for physicians who read EKGs infrequently 2
  • Consider periodic self-study or continuing medical education to ensure skills remain current 2
  • Recognize that successful completion of residency, board certification, and Advanced Cardiac Life Support training provides a reasonable foundation for bedside EKG interpretation in routine and emergency situations 2

References

Guideline

EKG Interpretation Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

The Electrocardiogram: Still a Useful Tool in the Primary Care Office.

The Medical clinics of North America, 2019

Research

The role of the ECG in diagnosis, risk estimation, and catheterization laboratory activation in patients with acute coronary syndromes: a consensus document.

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2014

Research

ECG diagnosis and classification of acute coronary syndromes.

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2014

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.