Should I administer the scheduled dose of Lantus (insulin glargine) 30 units and Lispro (insulin lispro) 6 units as per the sliding scale protocol for a patient with hyperglycemia?

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Administering Insulin for a Patient with Blood Glucose of 279 mg/dL at 2 AM

Yes, you should administer both the scheduled Lantus 30 units and Lispro 6 units sliding scale for this patient with a blood glucose of 279 mg/dL. This is consistent with current hospital diabetes management guidelines.

Rationale for Administration

  • Basal insulin (Lantus/insulin glargine) plus correction insulin (Lispro/insulin lispro) is the preferred treatment for hospitalized patients with hyperglycemia, especially when blood glucose levels are elevated above target range 1
  • A blood glucose of 279 mg/dL indicates significant hyperglycemia that requires treatment to prevent further metabolic derangement 1
  • Using only sliding scale insulin without basal insulin (Lantus) is strongly discouraged in hospital settings as it leads to poor glycemic control 1
  • Delaying insulin therapy in patients not achieving glycemic goals is not recommended (B rating) 1

Insulin Administration Guidelines

  • For hospitalized patients with hyperglycemia, a regimen with both basal insulin (Lantus) and correction components (Lispro) is the standard of care 1
  • Lantus (insulin glargine) provides essential background insulin coverage for 24 hours 1, 2
  • Lispro (insulin lispro) is a rapid-acting insulin analog that helps address immediate hyperglycemia 3, 4
  • For patients not eating (as may be the case at 2 AM), glucose monitoring every 4-6 hours with appropriate insulin administration is recommended 1

Important Considerations

  • After administering insulin, continue to monitor the patient for potential hypoglycemia, especially during nighttime hours 1
  • Document the administration and subsequent blood glucose readings in the medical record 1
  • Ensure the scheduled 7:30 AM blood glucose check is performed to evaluate the effectiveness of the insulin administration 1
  • Verify that the patient has no contraindications to receiving the prescribed insulin doses 1

Hypoglycemia Prevention

  • Be aware of the risk of hypoglycemia, particularly during overnight hours 1
  • Have hypoglycemia treatment protocols readily available 1
  • If hypoglycemia (<70 mg/dL) occurs after administration, follow your institution's hypoglycemia management protocol and document the episode 1
  • Consider reviewing the insulin regimen if repeated hypoglycemic episodes occur 1

Common Pitfalls to Avoid

  • Withholding basal insulin (Lantus) when blood glucose is elevated is a common error that leads to worsening hyperglycemia 1
  • Using only sliding scale insulin (Lispro) without basal insulin leads to poor glycemic control and glucose variability 1
  • Delaying insulin administration when indicated can lead to worsening hyperglycemia and metabolic complications 1
  • Failing to monitor blood glucose after insulin administration increases risk of undetected hypoglycemia 1

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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