Meralgia Paresthetica: This condition is characterized by numbness, tingling, and burning pain in the outer part of the thigh due to compression of the lateral femoral cutaneous nerve. It's common in adults and can be caused by tight clothing, obesity, or direct pressure on the nerve.

Lumbar Radiculopathy: Nerve root irritation or compression in the lumbar spine can cause radiating pain, numbness, or tingling in the thigh. This could be due to a herniated disc, spinal stenosis, or spondylolisthesis.
Peripheral Neuropathy: Conditions like diabetes, alcohol abuse, or vitamin deficiencies can lead to peripheral neuropathy, which may cause burning or numbness sensations in the thighs.
Piriformis Syndrome: Compression of the sciatic nerve by the piriformis muscle can cause pain, numbness, and tingling in the thigh and leg.

Spinal Cord Compression: Conditions like spinal tumors, epidural abscess, or spinal cord infarction can cause numbness, weakness, and loss of bladder or bowel control. Early diagnosis is crucial to prevent permanent damage.
Deep Vein Thrombosis (DVT): Although less common, DVT can cause swelling, warmth, and pain in the thigh, which might be mistaken for a neurological condition.
Abdominal Aortic Aneurysm: A large aneurysm can compress nearby nerves, causing pain, numbness, or tingling in the thigh.

Neurosyphilis: A rare condition caused by syphilis infection, which can lead to numbness, tingling, and pain in the thighs.
Vasculitis: Inflammation of blood vessels can cause numbness, pain, and weakness in the thighs, although this is a rare condition.
Tumor or Cyst: Rarely, a tumor or cyst in the thigh or spine can compress nerves, causing numbness, pain, or tingling sensations.