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Last updated: October 6, 2025View editorial policy

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Differential Diagnosis for White Discharge in a 6-Month-Old Baby's Penis

Single Most Likely Diagnosis

  • Physiological Smegma: This is a common and normal finding in infants, caused by the accumulation of dead skin cells, oil, and other substances under the foreskin. It's usually white or yellowish in color and doesn't typically cause any symptoms.

Other Likely Diagnoses

  • Balanitis: An inflammation of the glans penis, which can be caused by infection or irritation. It's more common in uncircumcised boys and can present with discharge.
  • Urethral Mucoid Discharge: A normal finding in newborns, caused by the presence of mucoid material in the urethra. However, if it persists or is accompanied by other symptoms, it may indicate an underlying issue.
  • Contact Dermatitis: An allergic reaction or irritation caused by soaps, diapers, or other substances coming into contact with the penis.

Do Not Miss Diagnoses

  • Gonococcal or Chlamydial Infection: Although less common in infants, these sexually transmitted infections can be transmitted from mother to child during birth. They require prompt treatment to prevent long-term complications.
  • Urinary Tract Infection (UTI): UTIs can present with discharge, fever, and other symptoms. In infants, they can be more serious and require immediate medical attention.

Rare Diagnoses

  • Warts or Other STDs: Although rare in infants, it's essential to consider the possibility of other sexually transmitted diseases, especially if there's a history of maternal infection.
  • Congenital Anomalies: Certain congenital conditions, such as hypospadias or epispadias, can increase the risk of urinary tract problems and discharge.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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