Price of Lifitegrast 5% Solution (Xiidra) in India
Based on the most recent evidence from 2025, the price of Lifitegrast 5% ophthalmic solution (Xiidra) in India is not specifically documented in the available medical literature and guidelines.
While the price information for Lifitegrast 5% solution in India is not directly provided in the available evidence, we can note several important aspects about this medication:
About Lifitegrast 5% Solution (Xiidra)
- Lifitegrast is a novel small molecule integrin antagonist that blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), which contributes to T-cell activation and migration in dry eye disease 1
- It was FDA approved in 2016 for the treatment of signs and symptoms of dry eye disease 2
- The medication is administered as eye drops twice daily 3
Clinical Efficacy in Indian Population
- A recent 2025 randomized, double-blind, active-controlled trial in Indian patients with dry eye disease demonstrated significantly more favorable outcomes with lifitegrast 5% compared to carboxymethylcellulose 0.5% 3
- The study showed improvements in eye dryness score, ocular discomfort score, ocular surface disease index, and tear film break-up time in Indian patients 3
Pricing Context
- While the US pricing data is available in medical guidelines (ranging from $338-$1,283 for various medications in the same therapeutic categories), specific Indian pricing for Lifitegrast is not provided 4
- Pharmaceutical pricing varies significantly between countries due to different regulatory frameworks, market conditions, and healthcare systems 4
Availability and Considerations
- The medication has demonstrated efficacy in Indian patients with dry eye disease 3
- Approximately 20.9% of dry eye disease patients receive lifitegrast treatment according to a survey of eyecare professionals in the USA and Canada 5
- The medication is generally well tolerated with most adverse events being mild to moderate in severity 6
Clinical Outcomes
- Treatment with lifitegrast has been associated with statistically significant improvements in matrix metalloproteinase-9 levels, ocular symptoms, corneal staining, and tear breakup time 7
- Global improvement and tolerability were found to be better with lifitegrast compared to carboxymethylcellulose in Indian patients 3
To obtain current and accurate pricing information for Lifitegrast 5% solution in India, it would be advisable to contact local pharmacies, pharmaceutical distributors, or the manufacturer directly.